METHODS: An experimental study was conducted with Wistar rats from July to December 2020. 3D tympanostomy tube models were designed, with technical specifications and tests performed on inexpensive 3D printers. The tympanostomy tube was inserted endoscopically.
RESULTS: Procedures were performed on five rats with implants in both ears. Pre-intervention pathologies, such as atical retraction and glue ear, were found. The PLA-printed tympanostomy tube showed improvement after adjustments. Histopathological results revealed significant middle and inner ear damage.
CONCLUSIONS: In our study, the design and 3D printing of implants fulfilled the desired functions when modified, with a height of 5 mm. Complications included PLA degradation and ear damage. There were no adverse events during observation, highlighting the need for further research on 3D-printed implants.
方法:2020年7月至12月对Wistar大鼠进行了实验研究。设计了三维鼓膜置管模型,在廉价的3D打印机上进行技术规格和测试。通过内窥镜插入鼓膜造口管。
结果:对五只双耳植入的大鼠进行了程序。干预前病理,如收缩和胶水耳朵,被发现了。调整后,PLA打印的鼓膜造口管显示出改善。组织病理学结果显示明显的中耳和内耳损伤。
结论:在我们的研究中,植入物的设计和3D打印在修改后达到了预期的功能,5毫米的高度。并发症包括PLA降解和耳朵损伤。观察期间无不良事件发生,强调需要进一步研究3D打印植入物。