Abstract：
OBJECTIVE: Guanyuan (CV4), Zhongji (CV3) and Sanyinjiao (SP6) are the most frequently used acupoints for treating neurogenic bladder after spinal cord injury (SCI). However, there has been no investigation to clarify the differences in effects of these acupoints in different types of neurogenic bladder.
METHODS: The study was structured with a randomized, two-phase cross over design with a washout period. A routine urodynamic examination was performed first, then, in the order of grouping, electroacupuncture was performed on CV4, CV3, and SP6, respectively，and urodynamic examination was performed to observe the changes of urodynamic indexes in real time.
RESULTS: When undergoing electroacupuncture at CV4, CV3, and SP6 in patients with neurogenic detrusor overactivity (DO), the bladder volume at the first occurrence of DO and maximum cystometric capacity increased (p < 0.05), but maximum detrusor pressure (Pdetmax) at DO decreased (p < 0.05), and the changes using CV4 and CV3 was more significantly than using SP6 (p < 0.05). And in patients with in neurogenic detrusor underactivity, there were no significant changes in maximum urinary flow rate and Pdetmax during urination (p > 0.05).
CONCLUSIONS: The immediate relief effect of electroacupuncture at CV4, CV3 on DO was greater than at SP6.
METHODS: The study was structured with a randomized, two-phase cross over design with a washout period. A routine urodynamic examination was performed first, then, in the order of grouping, electroacupuncture was performed on CV4, CV3, and SP6, respectively，and urodynamic examination was performed to observe the changes of urodynamic indexes in real time.
RESULTS: When undergoing electroacupuncture at CV4, CV3, and SP6 in patients with neurogenic detrusor overactivity (DO), the bladder volume at the first occurrence of DO and maximum cystometric capacity increased (p < 0.05), but maximum detrusor pressure (Pdetmax) at DO decreased (p < 0.05), and the changes using CV4 and CV3 was more significantly than using SP6 (p < 0.05). And in patients with in neurogenic detrusor underactivity, there were no significant changes in maximum urinary flow rate and Pdetmax during urination (p > 0.05).
CONCLUSIONS: The immediate relief effect of electroacupuncture at CV4, CV3 on DO was greater than at SP6.
摘要：
目的：关元（CV4），中济（CV3）和三阴交（SP6）是治疗脊髓损伤（SCI）后神经源性膀胱最常用的穴位。然而,目前还没有研究阐明这些穴位在不同类型神经源性膀胱中的作用差异。
方法：本研究采用随机，两阶段交叉设计与冲洗期。首先进行常规尿动力学检查，然后,按照分组的顺序，分别对CV4、CV3、SP6进行电针，并进行尿动力学检查，实时观察尿动力学指标的变化。
结果：在神经性逼尿肌过度活动（DO）患者中接受CV4，CV3和SP6电针时，首次出现DO时的膀胱容量和最大膀胱容量增加（p<0.05），但DO时最大逼尿肌压力(Pdetmax)下降(p<0.05)，使用CV4和CV3的变化比使用SP6的变化更显著(p<0.05)。在神经源性逼尿肌活动不足的患者中，排尿时最大尿流率和Pdetmax无明显变化(p>0.05)。
结论：电针对CV4，CV3对DO的即时缓解作用大于SP6。
方法：本研究采用随机，两阶段交叉设计与冲洗期。首先进行常规尿动力学检查，然后,按照分组的顺序，分别对CV4、CV3、SP6进行电针，并进行尿动力学检查，实时观察尿动力学指标的变化。
结果：在神经性逼尿肌过度活动（DO）患者中接受CV4，CV3和SP6电针时，首次出现DO时的膀胱容量和最大膀胱容量增加（p<0.05），但DO时最大逼尿肌压力(Pdetmax)下降(p<0.05)，使用CV4和CV3的变化比使用SP6的变化更显著(p<0.05)。在神经源性逼尿肌活动不足的患者中，排尿时最大尿流率和Pdetmax无明显变化(p>0.05)。
结论：电针对CV4，CV3对DO的即时缓解作用大于SP6。
