PDF(Pubmed)
Abstract：
Post-intensive care syndrome (PICS) is the term used to describe the decline in the physical, cognitive, and/or mental condition of individuals who have been discharged from the intensive care unit (ICU). This complication could result in a significant reduction in quality of life, with some patients experiencing symptoms of prolonged weakness, depression, anxiety, and post-traumatic stress disorder (PTSD). Intensive care advancement over the years has resulted in an increase in ICU survival rates and a proportional increase in PICS, creating a need for more in-depth research into the prevention and management of the disease. Hence, this study aims to examine the present body of literature on PICS, encompassing its underlying physiological processes and elements that contribute to its development, methods for evaluating and diagnosing the condition, current treatment choices as well as potential new approaches, and the constraints in managing PICS and the necessity for further investigation. In this article, studies were compiled from several databases, including, but not limited to, Google Scholar, PubMed, and Cochrane Library. These studies were reviewed, and their data were used to highlight important aspects regarding the efficacy of current PICS screening tools, the optimization and limitations of both pharmacologic and non-pharmacologic treatment methods, and the feasibility and safety of emerging treatments and technologies. The major conclusions of this review were centered around the need for multidisciplinary management of PICS. From pharmacological management using analgesia to non-pharmacological management using early mobilization and exercise therapy, the effective treatment of PICS requires a multifaceted approach. Patient follow-up and its importance were touched upon, including strategies and policies to bolster proper follow-up, thereby increasing favorable outcomes. Lastly, the importance of family involvement and the increased need for research into this topic were highlighted.
摘要：
重症监护后综合征（PICS）是用于描述身体素质下降的术语，认知，和/或已从重症监护病房（ICU）出院的个人的精神状况。这种并发症可能导致生活质量显著下降，一些患者出现长期虚弱的症状，抑郁症,焦虑,和创伤后应激障碍（PTSD）。多年来，重症监护的进步导致了ICU生存率的提高和PICS的成比例增加，需要对疾病的预防和管理进行更深入的研究。因此，本研究旨在考察目前有关PICS的文献，包含其潜在的生理过程和有助于其发展的元素，评估和诊断病情的方法，当前的治疗选择以及潜在的新方法，以及管理PICS的制约因素和进一步调查的必要性。在这篇文章中,研究是从几个数据库中汇编出来的，包括,但不限于,谷歌学者，PubMed,科克伦图书馆对这些研究进行了回顾，他们的数据被用来突出当前PICS筛查工具功效的重要方面，药物和非药物治疗方法的优化和局限性，以及新兴治疗和技术的可行性和安全性。本综述的主要结论集中在对PICS的多学科管理的需求上。从使用镇痛的药物管理到使用早期动员和运动疗法的非药物管理，PICS的有效治疗需要多方面的方法。患者随访及其重要性被触及，包括支持适当后续行动的战略和政策，从而增加有利的结果。最后,强调了家庭参与的重要性以及对该主题研究的需求增加。
