PDF(Pubmed)
Abstract：
UNASSIGNED: The objective of this study was to assess the global burden of disease for developmental and intellectual disabilities caused by iodine deficiency from 1990 to 2019.
UNASSIGNED: Using data from the global burden of disease (GBD) 2019, we conducted a cross-country inequity analysis to examine the worldwide burden of developmental and intellectual disabilities caused by the issue of iodine deficiency from 1990 to 2019. Absolute and relative inequality were assessed by the slope index of inequality and the concentration index, respectively. After summarising the latest evidence, we also projected the age-standardized prevalence and years lived with disability (YLD) rates up to 2030 using the BAPC and INLA packages in R statistical software.
UNASSIGNED: In 2019, the global age-standardized prevalence and YLD rates for developmental and intellectual disabilities due to iodine deficiency were 22.54 per 100,000 population (95% UI 14.47 to 29.23) and 4.12 per 100,000 population (95% UI 2.25 to 6.4), respectively. From 1990 to 2019, the age-standardized prevalence and YLD rates of developmental and intellectual disabilities due to iodine deficiency decreased significantly. Geographic distribution showed that areas with lower socio-demographic indices (SDI) were the most affected. The correlation between higher SDI and lower prevalence highlights the role of economic and social factors in the prevalence of the disease. Cross-national inequity analysis shows that disparities persist despite improvements in health inequalities. In addition, projections suggest that the disease burden may decline until 2030.
UNASSIGNED: This research underscores the necessity for targeted interventions, such as enhancing iodine supplementation and nutritional education, especially in areas with lower SDI. We aim to provide a foundation for policymakers further to research effective preventative and potential alternative treatment strategies.
UNASSIGNED: Using data from the global burden of disease (GBD) 2019, we conducted a cross-country inequity analysis to examine the worldwide burden of developmental and intellectual disabilities caused by the issue of iodine deficiency from 1990 to 2019. Absolute and relative inequality were assessed by the slope index of inequality and the concentration index, respectively. After summarising the latest evidence, we also projected the age-standardized prevalence and years lived with disability (YLD) rates up to 2030 using the BAPC and INLA packages in R statistical software.
UNASSIGNED: In 2019, the global age-standardized prevalence and YLD rates for developmental and intellectual disabilities due to iodine deficiency were 22.54 per 100,000 population (95% UI 14.47 to 29.23) and 4.12 per 100,000 population (95% UI 2.25 to 6.4), respectively. From 1990 to 2019, the age-standardized prevalence and YLD rates of developmental and intellectual disabilities due to iodine deficiency decreased significantly. Geographic distribution showed that areas with lower socio-demographic indices (SDI) were the most affected. The correlation between higher SDI and lower prevalence highlights the role of economic and social factors in the prevalence of the disease. Cross-national inequity analysis shows that disparities persist despite improvements in health inequalities. In addition, projections suggest that the disease burden may decline until 2030.
UNASSIGNED: This research underscores the necessity for targeted interventions, such as enhancing iodine supplementation and nutritional education, especially in areas with lower SDI. We aim to provide a foundation for policymakers further to research effective preventative and potential alternative treatment strategies.
摘要：
■这项研究的目的是评估1990年至2019年由碘缺乏引起的发育和智力障碍的全球疾病负担。
■使用来自2019年全球疾病负担（GBD）的数据，我们进行了一项跨国不平等分析，以检查1990年至2019年碘缺乏问题造成的全球发育和智力障碍负担。绝对不等式和相对不等式分别通过斜率指数和集中度指数进行评估,分别。在总结了最新的证据之后,我们还使用R统计软件中的BAPC和INLA软件包预测了截至2030年的年龄标准化患病率和残疾年龄(YLD)率.
■2019年，全球因碘缺乏而导致的发育和智力障碍的年龄标准化患病率和YLD率为每100,000人口22.54（95％UI14.47至29.23）和每100,000人口4.12（95％UI2.25至6.4）。分别。从1990年到2019年，由于碘缺乏导致的发育和智力障碍的年龄标准化患病率和YLD比率显着下降。地理分布表明，社会人口指数（SDI）较低的地区受影响最大。较高的SDI和较低的患病率之间的相关性突出了经济和社会因素在该疾病患病率中的作用。跨国不平等分析表明，尽管健康不平等有所改善，但差距仍然存在。此外,预测表明，疾病负担可能会下降到2030年。
■这项研究强调了有针对性干预措施的必要性，例如加强补充碘和营养教育，特别是在SDI较低的地区。我们的目标是为政策制定者进一步研究有效的预防和潜在的替代治疗策略提供基础。
■使用来自2019年全球疾病负担（GBD）的数据，我们进行了一项跨国不平等分析，以检查1990年至2019年碘缺乏问题造成的全球发育和智力障碍负担。绝对不等式和相对不等式分别通过斜率指数和集中度指数进行评估,分别。在总结了最新的证据之后,我们还使用R统计软件中的BAPC和INLA软件包预测了截至2030年的年龄标准化患病率和残疾年龄(YLD)率.
■2019年，全球因碘缺乏而导致的发育和智力障碍的年龄标准化患病率和YLD率为每100,000人口22.54（95％UI14.47至29.23）和每100,000人口4.12（95％UI2.25至6.4）。分别。从1990年到2019年，由于碘缺乏导致的发育和智力障碍的年龄标准化患病率和YLD比率显着下降。地理分布表明，社会人口指数（SDI）较低的地区受影响最大。较高的SDI和较低的患病率之间的相关性突出了经济和社会因素在该疾病患病率中的作用。跨国不平等分析表明，尽管健康不平等有所改善，但差距仍然存在。此外,预测表明，疾病负担可能会下降到2030年。
■这项研究强调了有针对性干预措施的必要性，例如加强补充碘和营养教育，特别是在SDI较低的地区。我们的目标是为政策制定者进一步研究有效的预防和潜在的替代治疗策略提供基础。
