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Abstract：
UNASSIGNED: Aims to provide an overview of the contemporary epidemiology of malignant orbital tumors by analyzing population-based incidence patterns across various regions worldwide.
UNASSIGNED: In this article, we retrieved orbital malignancy data from the MEDLINE database and analyzed the incidence and prevalence of orbital malignancies worldwide. We performed the literature search by searching on the Mesh terms for malignant orbital tumors (\"orbital\", \"tumor\", \"lymphoma\", \"malignant\", \"cancer\", \"incidence\", and \"epidemiology\"). All included studies were published between 1993 and 2023 and were written in English.
UNASSIGNED: Ocular or ophthalmic lymphoma most frequently occurred in the orbit, with a prevalence ranging from 47% to 54%. The incidence of malignant orbital tumors was increasing in the USA (2.0 per million (1981-1993), Netherlands (0.86 (1981-1985) to 2.49 (2001-2005) per million) and South Korea (0.3-0.8 per million (1999-2016)), respectively. Ophthalmic lymphoma which includes orbit lymphoma was increasing in Canada (0.17-1.47 per million (1992-2010)), Denmark (0.86 per million (1981-1985) to 2.49 per million (2001-2005)), respectively.
UNASSIGNED: The predominant primary malignant orbital tumor in adults was lymphoma. Ocular or ophthalmic lymphoma most frequently occured in the orbit. The limited data available suggested an increasing trend in the incidence of malignant orbital tumors in each country included, which were mainly attributed to the increase in lymphoma. Generally, incidence rates were found to increase with advancing age, with no difference between males and females.
UNASSIGNED: In this article, we retrieved orbital malignancy data from the MEDLINE database and analyzed the incidence and prevalence of orbital malignancies worldwide. We performed the literature search by searching on the Mesh terms for malignant orbital tumors (\"orbital\", \"tumor\", \"lymphoma\", \"malignant\", \"cancer\", \"incidence\", and \"epidemiology\"). All included studies were published between 1993 and 2023 and were written in English.
UNASSIGNED: Ocular or ophthalmic lymphoma most frequently occurred in the orbit, with a prevalence ranging from 47% to 54%. The incidence of malignant orbital tumors was increasing in the USA (2.0 per million (1981-1993), Netherlands (0.86 (1981-1985) to 2.49 (2001-2005) per million) and South Korea (0.3-0.8 per million (1999-2016)), respectively. Ophthalmic lymphoma which includes orbit lymphoma was increasing in Canada (0.17-1.47 per million (1992-2010)), Denmark (0.86 per million (1981-1985) to 2.49 per million (2001-2005)), respectively.
UNASSIGNED: The predominant primary malignant orbital tumor in adults was lymphoma. Ocular or ophthalmic lymphoma most frequently occured in the orbit. The limited data available suggested an increasing trend in the incidence of malignant orbital tumors in each country included, which were mainly attributed to the increase in lymphoma. Generally, incidence rates were found to increase with advancing age, with no difference between males and females.
摘要：
■旨在通过分析全球各个地区基于人群的发病率模式，提供对眼眶恶性肿瘤当代流行病学的概述。
■在本文中，我们从MEDLINE数据库检索了眼眶恶性肿瘤数据,并分析了全世界眼眶恶性肿瘤的发病率和患病率.我们通过在网状术语上搜索恶性眼眶肿瘤（“眼眶”，\"肿瘤\",“淋巴瘤”，“恶性”，\"癌症\",\"发生率\",和“流行病学”)。所有纳入的研究均在1993年至2023年之间发表，并以英文撰写。
■眼或眼科淋巴瘤最常见于眼眶，患病率从47%到54%不等。在美国，恶性眼眶肿瘤的发病率正在增加（百万分之2.0（1981-1993），荷兰（每百万0.86（1981-1985）至2.49（2001-2005））和韩国（每百万0.3-0.8（1999-2016）），分别。在加拿大，包括眼眶淋巴瘤在内的眼科淋巴瘤正在增加（0.17-1.47/百万（1992-2010）），丹麦（百万分之0.86（1981-1985）至百万分之2.49（2001-2005）），分别。
■成人主要的原发性恶性眼眶肿瘤是淋巴瘤。眼或眼科淋巴瘤最常见于眼眶。现有的有限数据表明，在包括在内的每个国家，恶性眼眶肿瘤的发病率呈上升趋势。这主要归因于淋巴瘤的增加。一般来说,发现发病率随着年龄的增长而增加，男性和女性之间没有区别。
■在本文中，我们从MEDLINE数据库检索了眼眶恶性肿瘤数据,并分析了全世界眼眶恶性肿瘤的发病率和患病率.我们通过在网状术语上搜索恶性眼眶肿瘤（“眼眶”，\"肿瘤\",“淋巴瘤”，“恶性”，\"癌症\",\"发生率\",和“流行病学”)。所有纳入的研究均在1993年至2023年之间发表，并以英文撰写。
■眼或眼科淋巴瘤最常见于眼眶，患病率从47%到54%不等。在美国，恶性眼眶肿瘤的发病率正在增加（百万分之2.0（1981-1993），荷兰（每百万0.86（1981-1985）至2.49（2001-2005））和韩国（每百万0.3-0.8（1999-2016）），分别。在加拿大，包括眼眶淋巴瘤在内的眼科淋巴瘤正在增加（0.17-1.47/百万（1992-2010）），丹麦（百万分之0.86（1981-1985）至百万分之2.49（2001-2005）），分别。
■成人主要的原发性恶性眼眶肿瘤是淋巴瘤。眼或眼科淋巴瘤最常见于眼眶。现有的有限数据表明，在包括在内的每个国家，恶性眼眶肿瘤的发病率呈上升趋势。这主要归因于淋巴瘤的增加。一般来说,发现发病率随着年龄的增长而增加，男性和女性之间没有区别。
