PDF(Pubmed)
Abstract：
UNASSIGNED: In recent decades, there has been an increase in early-onset colorectal cancer, the need to screen individuals younger than 50 years of age, and the presence of histopathological differences remains unclear. The objective of this study was to explore the occurrence of polyps in both young adults and older individuals and to examine their potential correlation with colorectal cancer.
UNASSIGNED: In this retrospective study conducted between July 1, 2018, and October 5, 2022, in the Pathology Laboratory, we designed a study based on the histopathological features of colorectal polyps evaluated by an experienced gastrointestinal pathologist based on the WHO 2019 classification.
UNASSIGNED: We evaluated 735 consecutive patients who underwent colonoscopic polypectomy between July 2018 and October 2022. The prevalence of cases under the age of 50 was 13.9%, and adults over the age of 50 was 86.1%. A total of 1269 polyps were detected, 1215 (95.7%) were epithelial polyps and 145 (11.9%) were epithelial polyps under the age of 50. One hundred four conventional adenomas and four intramucosal carcinomas were detected in cases younger than 50 years. The patients in the low-risk adenoma group was 57%, and the rate of patients in the high-risk adenoma group was 14.9%. Overall, polyps were most common in the sigmoid colon and there was a statistically significant difference between detecting tubular adenomas in the sigmoid colon (P=0.04).
UNASSIGNED: Our current results confirm the detection of sporadic colorectal adenomas and advanced neoplasia in young adults.It is important to establish professional community guidelines for surveillance colonoscopy in these age groups.
UNASSIGNED: In this retrospective study conducted between July 1, 2018, and October 5, 2022, in the Pathology Laboratory, we designed a study based on the histopathological features of colorectal polyps evaluated by an experienced gastrointestinal pathologist based on the WHO 2019 classification.
UNASSIGNED: We evaluated 735 consecutive patients who underwent colonoscopic polypectomy between July 2018 and October 2022. The prevalence of cases under the age of 50 was 13.9%, and adults over the age of 50 was 86.1%. A total of 1269 polyps were detected, 1215 (95.7%) were epithelial polyps and 145 (11.9%) were epithelial polyps under the age of 50. One hundred four conventional adenomas and four intramucosal carcinomas were detected in cases younger than 50 years. The patients in the low-risk adenoma group was 57%, and the rate of patients in the high-risk adenoma group was 14.9%. Overall, polyps were most common in the sigmoid colon and there was a statistically significant difference between detecting tubular adenomas in the sigmoid colon (P=0.04).
UNASSIGNED: Our current results confirm the detection of sporadic colorectal adenomas and advanced neoplasia in young adults.It is important to establish professional community guidelines for surveillance colonoscopy in these age groups.
摘要：
■近几十年来，早发性结肠直肠癌的发病率有所上升,需要筛查50岁以下的人，组织病理学差异的存在尚不清楚。这项研究的目的是探讨年轻人和老年人中息肉的发生，并检查其与结直肠癌的潜在相关性。
■在2018年7月1日至2022年10月5日之间在病理学实验室进行的这项回顾性研究中，我们设计了一项基于有经验的胃肠道病理学家根据WHO2019分类评估的结直肠息肉组织病理学特征的研究.
■我们评估了2018年7月至2022年10月期间接受结肠镜息肉切除术的735例连续患者。50岁以下病例的患病率为13.9%,50岁以上的成年人占86.1%。共检出1269个息肉,年龄在50岁以下的上皮性息肉1215例（95.7%），上皮性息肉145例（11.9%）。在50岁以下的病例中发现了104例常规腺瘤和4例粘膜内癌。低危腺瘤组患者为57%,高危腺瘤组患者的发生率为14.9%。总的来说,息肉在乙状结肠中最常见,在乙状结肠中检出管状腺瘤之间存在统计学差异(P=0.04).
■我们目前的结果证实了在年轻人中检测到散发性结直肠腺瘤和晚期瘤形成。在这些年龄组中，建立专业的社区结肠镜检查监测指南非常重要。
■在2018年7月1日至2022年10月5日之间在病理学实验室进行的这项回顾性研究中，我们设计了一项基于有经验的胃肠道病理学家根据WHO2019分类评估的结直肠息肉组织病理学特征的研究.
■我们评估了2018年7月至2022年10月期间接受结肠镜息肉切除术的735例连续患者。50岁以下病例的患病率为13.9%,50岁以上的成年人占86.1%。共检出1269个息肉,年龄在50岁以下的上皮性息肉1215例（95.7%），上皮性息肉145例（11.9%）。在50岁以下的病例中发现了104例常规腺瘤和4例粘膜内癌。低危腺瘤组患者为57%,高危腺瘤组患者的发生率为14.9%。总的来说,息肉在乙状结肠中最常见,在乙状结肠中检出管状腺瘤之间存在统计学差异(P=0.04).
■我们目前的结果证实了在年轻人中检测到散发性结直肠腺瘤和晚期瘤形成。在这些年龄组中，建立专业的社区结肠镜检查监测指南非常重要。
