PDF(Pubmed)
Abstract：
UNASSIGNED: To investigate the physical properties of commercially available multipurpose soft contact lens solutions in Ghana.
UNASSIGNED: pH (Kelilong ICL-099 pH meter, China), osmolality (OSMOMAT 3000, GONOTEC, Germany), surface tension (Sigma 700 Tensiometer, Sweden), and viscosity (CFOC-200 Viscometer, Cannon Company, USA) of various soft contact lens multipurpose solutions (MPS) were measured in triplicates at room temperature. Viscosity measurements were also taken at 34 °C ocular surface temperature. The solutions examined were Opti-Free Replenish (OFR), Trufresh (TF), Avizor (AV), Freshlook (FL), and Refresh (RF).
UNASSIGNED: Several solutions were largely hypo-osmotic in the range of 108-231 mOsm/kg, the exception being Avizor, which had osmolality values that were closer to human tears (301 ± 0.58 mOsm/kg). The range of pH values of the solutions (6.33-8.24, mean (SD) = 7.53 ± 0.18) fell within the reported tolerable range for the ocular surface (6.20-9.00). Surface tension values ranged from 35.86 to 42.27 mNm with a mean of 38.49 ± 2.32 mNm. The average viscosity of most solutions at room temperature (25 °C) was 1.44 ± 0.49 cP with a range of 1.04-2.15 cP. Significantly lower values ranging from 0.79 to 1.58 cP were obtained at ocular surface temperature (34 °C), p = 0.0001).
UNASSIGNED: The physical properties of many of the solutions used as MPS in Ghana are markedly variable. Nevertheless, pH, surface tension, and viscosity fall within the acceptable limits of ocular physiological tolerance; except for osmolality, which majority were outside the reported tolerable range for the ocular surface. This information may partly explain the reason some patients exhibit strong preferences for certain care systems and should aid clinical decision-making when prescribing eye care systems to patients.
UNASSIGNED: pH (Kelilong ICL-099 pH meter, China), osmolality (OSMOMAT 3000, GONOTEC, Germany), surface tension (Sigma 700 Tensiometer, Sweden), and viscosity (CFOC-200 Viscometer, Cannon Company, USA) of various soft contact lens multipurpose solutions (MPS) were measured in triplicates at room temperature. Viscosity measurements were also taken at 34 °C ocular surface temperature. The solutions examined were Opti-Free Replenish (OFR), Trufresh (TF), Avizor (AV), Freshlook (FL), and Refresh (RF).
UNASSIGNED: Several solutions were largely hypo-osmotic in the range of 108-231 mOsm/kg, the exception being Avizor, which had osmolality values that were closer to human tears (301 ± 0.58 mOsm/kg). The range of pH values of the solutions (6.33-8.24, mean (SD) = 7.53 ± 0.18) fell within the reported tolerable range for the ocular surface (6.20-9.00). Surface tension values ranged from 35.86 to 42.27 mNm with a mean of 38.49 ± 2.32 mNm. The average viscosity of most solutions at room temperature (25 °C) was 1.44 ± 0.49 cP with a range of 1.04-2.15 cP. Significantly lower values ranging from 0.79 to 1.58 cP were obtained at ocular surface temperature (34 °C), p = 0.0001).
UNASSIGNED: The physical properties of many of the solutions used as MPS in Ghana are markedly variable. Nevertheless, pH, surface tension, and viscosity fall within the acceptable limits of ocular physiological tolerance; except for osmolality, which majority were outside the reported tolerable range for the ocular surface. This information may partly explain the reason some patients exhibit strong preferences for certain care systems and should aid clinical decision-making when prescribing eye care systems to patients.
摘要：
■研究加纳市售多用途软性隐形眼镜溶液的物理性质。
■pH（KelilongICL-099pH计，中国),渗透压(OSMOMAT3000，GONOTEC，德国),表面张力(Sigma700张力计，瑞典),和粘度(CFOC-200粘度计，Cannon公司,USA）的各种软性隐形眼镜多用途溶液（MPS）在室温下一式三份进行了测量。还在34°C眼表温度下进行粘度测量。检查的解决方案是无Opti-FreeReplenish(OFR)，Trufresh(TF),Avizor(AV),Freshlook（FL），和刷新（RF）。
■几种溶液在108-231mOsm/kg的范围内基本上是低渗的，例外是阿维佐尔，其具有更接近人类眼泪的渗透压值(301±0.58mOsm/kg)。溶液的pH值范围（6.33-8.24，平均值（SD）=7.53±0.18）落在报告的眼表容许范围内（6.20-9.00）。表面张力值范围为35.86至42.27mNm,平均值为38.49±2.32mNm。大多数溶液在室温（25°C）下的平均粘度为1.44±0.49cP，范围为1.04-2.15cP。在眼表温度（34°C）下获得了0.79至1.58cP的显着较低值，p=0.0001)。
■在加纳用作MPS的许多溶液的物理性质是明显可变的。然而，pH值,表面张力,和粘度落在眼睛生理耐受的可接受范围内；除了渗透压，其中大部分超出了眼表报告的容许范围。这些信息可能部分解释了一些患者对某些护理系统表现出强烈偏好的原因，并且在向患者开具眼部护理系统时应该帮助临床决策。
■pH（KelilongICL-099pH计，中国),渗透压(OSMOMAT3000，GONOTEC，德国),表面张力(Sigma700张力计，瑞典),和粘度(CFOC-200粘度计，Cannon公司,USA）的各种软性隐形眼镜多用途溶液（MPS）在室温下一式三份进行了测量。还在34°C眼表温度下进行粘度测量。检查的解决方案是无Opti-FreeReplenish(OFR)，Trufresh(TF),Avizor(AV),Freshlook（FL），和刷新（RF）。
■几种溶液在108-231mOsm/kg的范围内基本上是低渗的，例外是阿维佐尔，其具有更接近人类眼泪的渗透压值(301±0.58mOsm/kg)。溶液的pH值范围（6.33-8.24，平均值（SD）=7.53±0.18）落在报告的眼表容许范围内（6.20-9.00）。表面张力值范围为35.86至42.27mNm,平均值为38.49±2.32mNm。大多数溶液在室温（25°C）下的平均粘度为1.44±0.49cP，范围为1.04-2.15cP。在眼表温度（34°C）下获得了0.79至1.58cP的显着较低值，p=0.0001)。
■在加纳用作MPS的许多溶液的物理性质是明显可变的。然而，pH值,表面张力,和粘度落在眼睛生理耐受的可接受范围内；除了渗透压，其中大部分超出了眼表报告的容许范围。这些信息可能部分解释了一些患者对某些护理系统表现出强烈偏好的原因，并且在向患者开具眼部护理系统时应该帮助临床决策。
