关键词: Analgesia Cesarean delivery Cesarean section Nerve block Neuraxial analgesia Opioid Pharmacology

来  源:   DOI:10.1007/s11916-024-01278-8

Abstract:
OBJECTIVE: With the increasing prevalence of cesarean section globally, the importance of perioperative analgesia for cesarean section is becoming increasingly evident. This article provides an overview and update on the current status of cesarean section worldwide and associated analgesic regimens.
RESULTS: Some recent studies unveiled potential association of neuraxial analgesia might be associated with children\'s autism, pharmacologic analgesia in obstetric will potentially gain some more attention. Various commonly used techniques and medications for analgesia in cesarean section are highlighted. While neuraxial administration of opioid remains the most classic method, the use of multimodal analgesia, particularly integration of nonsteroidal anti-inflammatory drugs, acetaminophen, peripheral nerve blocks has provided additional and better options for patients who are not suitable for intrathecal and neuraxial techniques and those experiencing severe pain postoperatively. Optimal pain management is crucial for achieving better clinical outcomes and optimal recovery, and with the continuous development of medications, more and better pharmacologic regimen will be available in the future.
摘要:
目的:随着全球剖宫产率的上升,剖宫产围手术期镇痛的重要性日益明显。本文概述和更新了世界范围内剖宫产的现状以及相关的镇痛方案。
结果:最近的一些研究揭示了神经轴镇痛的潜在关联可能与儿童自闭症有关,产科药物镇痛可能会引起更多关注。强调了剖宫产镇痛的各种常用技术和药物。虽然阿片类药物的神经轴给药仍然是最经典的方法,多模式镇痛的使用,特别是非甾体抗炎药的整合,对乙酰氨基酚,周围神经阻滞为不适合鞘内和神经轴技术的患者以及术后出现严重疼痛的患者提供了额外和更好的选择。最佳的疼痛管理对于实现更好的临床结果和最佳康复至关重要。随着药物的不断发展,将来会有更多更好的药物治疗方案。
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