关键词: Circulating plasma cells Flow cytometry Plasma cell disease

Mesh : Flow Cytometry / methods Humans Plasma Cells Multiple Myeloma / diagnosis blood China Paraproteinemias / diagnosis blood Monoclonal Gammopathy of Undetermined Significance / diagnosis blood Consensus East Asian People

来  源:   DOI:10.3760/cma.j.cn121090-20240117-00026

Abstract:
Flow cytometry plays an important role in the diagnosis and treatment of plasma cell diseases, particularly in the detection of circulating plasma cells (CPCs) in the peripheral blood. A consensus about the normalized use of flow cytometry in detection of CPCs in peripheral blood in clinical practice has been achieved. This consensus is founded on evidence-based principles, which elucidates the timing and value of flow cytometry for the detection of CPCs in the monoclonal gammopathy of undetermined significance, smoldering myeloma, multiple myeloma, and plasma cell leukemia and standardizes flow cytometry in the detection of CPCs in plasma cell diseases.
流式细胞术检测外周血循环浆细胞(circulating plasma cells,CPCs)在浆细胞病的诊疗中已经展示出了重要价值。为促进流式细胞术检测CPCs在临床中的规范使用,特制定本共识。本共识依据循证原则,明确了意义未明的单克隆免疫球蛋白血症、冒烟型骨髓瘤、多发性骨髓瘤和浆细胞白血病进行CPCs检测的时机与价值,并对CPCs的流式细胞术检测方法进行规范。.
摘要:
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