Abstract：
Metal-organic gels (MOGs) are a type of metal-organic colloid material with a large specific surface area, loose porous structure, and open metal active sites. In this work, FeNi-MOGs were synthesized by the simple one-step static method, using Fe(III) and Ni(II) as the central metal ions and terephthalic acid as the organic ligand. The prepared FeNi-MOGs could effectively catalyze the chemiluminescence of luminol without the involvement of H2O2, which exhibited good catalytic activity. Then, the multifunctional detected platform was constructed for the detection of GSH and Hg2+, based on the antioxidant capacity of GSH, and the strong affinity between mercury ion (Hg2+) and GSH which inactivated the antioxidant capacity of GSH. The experimental limits of detection (LOD) for GSH and Hg2+ were 76 nM and 210 nM, and the detection ranges were 2-100 μM and 8-4000 μM, respectively. The as-proposed sensor had good performance in both detection limit and detection range of GSH and Hg2+, which fully met the needs of daily life. Surprisingly, the sensor had low detection limits and an extremely wide detection range for Hg2+, spanning five orders of magnitude. Furthermore, the detection of mercury ions in actual lake water and GSH in human serum showed good results, with recovery rates ranging from 90.10 % to 105.37 %, which proved that the method was accurate and reliable. The as-proposed sensor had great potential as the platform for GSH and Hg2+ detection applications.
摘要：
金属有机凝胶(MOGs)是一种具有较大比表面积的金属有机胶体材料,松散的多孔结构，和开放的金属活性位点。在这项工作中,FeNi-MOGs通过简单的一步静态法合成，使用Fe(III)和Ni(II)作为中心金属离子和对苯二甲酸作为有机配体。所制备的FeNi-MOGs能有效催化鲁米诺的化学发光,且无H2O2的参与,表现出良好的催化活性。然后，构建了检测GSH和Hg2+的多功能检测平台,基于GSH的抗氧化能力，汞离子(Hg2+)与GSH有较强的亲和力,使GSH的抗氧化能力失活。GSH和Hg2+的实验检测限(LOD)分别为76nM和210nM,检测范围为2-100μM和8-4000μM，分别。该传感器对GSH和Hg2+的检测限和检测范围均具有良好的性能,完全满足了日常生活的需要。令人惊讶的是,该传感器对Hg2+具有较低的检测限和极宽的检测范围，跨越五个数量级。此外，实际湖水中汞离子和人血清中GSH的检测结果良好,回收率从90.10%到105.37%，证明该方法准确可靠。所提出的传感器具有作为GSH和Hg2检测应用平台的巨大潜力。
