Abstract：
OBJECTIVE: The aim of this study was to compare the accuracy of colonoscopy (CS) and CT colonography (CTC) in the measurement of colorectal polyps using pathological size as a reference.
METHODS: The analysis included 61 colorectal polyps in 28 patients who underwent preoperative CTC at our institution. All polyps were endoscopically resected. Polyp sizes were measured by CS and CTC. Endoscopic polyp size was extracted from endoscopy records written by one of two endoscopists (A with 11 and B with 6 years of endoscopic experience, respectively), who estimated the size visually/categorically without any measuring devices. After matching the location, the polyp size was measured on CTC using manual three-dimensional (3D) measurement on a workstation. The sizes of resected polyps were also measured after pathological inspection. Differences of the polyp size between CTC and histology, and between CS and histology were compared using paired t tests. Differences in measurement between the two endoscopists were also analyzed.
RESULTS: The mean diameters of polyps measured using CS, CTC, and pathology were 10.5 mm, 9.2 mm, and 8.4 mm, respectively. There was a significant correlation between CS and pathology, as well as between CTC and pathology (both P < 0.0001). The correlation coefficient for CS (r = 0.86) was lower than that for CTC (r = 0.96). The correlations between CS and pathology for endoscopists A and B were 0.90 and 0.89, respectively.
CONCLUSIONS: Measurements of polyp size using CTC were closer to the pathological measurements compared to those by CS, which exhibited greater variability. This suggests that CTC may be more suitable for polyp size measurements in the clinical setting if patients undergo CTC concurrently with colonoscopy.
METHODS: The analysis included 61 colorectal polyps in 28 patients who underwent preoperative CTC at our institution. All polyps were endoscopically resected. Polyp sizes were measured by CS and CTC. Endoscopic polyp size was extracted from endoscopy records written by one of two endoscopists (A with 11 and B with 6 years of endoscopic experience, respectively), who estimated the size visually/categorically without any measuring devices. After matching the location, the polyp size was measured on CTC using manual three-dimensional (3D) measurement on a workstation. The sizes of resected polyps were also measured after pathological inspection. Differences of the polyp size between CTC and histology, and between CS and histology were compared using paired t tests. Differences in measurement between the two endoscopists were also analyzed.
RESULTS: The mean diameters of polyps measured using CS, CTC, and pathology were 10.5 mm, 9.2 mm, and 8.4 mm, respectively. There was a significant correlation between CS and pathology, as well as between CTC and pathology (both P < 0.0001). The correlation coefficient for CS (r = 0.86) was lower than that for CTC (r = 0.96). The correlations between CS and pathology for endoscopists A and B were 0.90 and 0.89, respectively.
CONCLUSIONS: Measurements of polyp size using CTC were closer to the pathological measurements compared to those by CS, which exhibited greater variability. This suggests that CTC may be more suitable for polyp size measurements in the clinical setting if patients undergo CTC concurrently with colonoscopy.
摘要：
目的：本研究的目的是比较结肠镜（CS）和CT结肠造影（CTC）在以病理大小为参考的结直肠息肉测量中的准确性。
方法：分析包括在我们机构接受术前CTC的28例患者的61例结直肠息肉。所有息肉均经内镜切除。通过CS和CTC测量息肉大小。从两位内窥镜医师之一撰写的内窥镜检查记录中提取内窥镜息肉大小（A为11，B为6年内窥镜检查经验，分别)，谁在没有任何测量设备的情况下视觉/分类地估计尺寸。匹配位置后，在CTC上使用工作站上的手动三维(3D)测量息肉大小.病理检查后，还测量了切除的息肉的大小。CTC和组织学之间息肉大小的差异，使用配对t检验比较CS和组织学之间的差异。还分析了两位内窥镜医师之间的测量差异。
结果：使用CS测量的息肉的平均直径，反恐委员会，病理为10.5毫米，9.2mm,和8.4毫米，分别。CS与病理有显著的相关性，以及CTC和病理之间（均P<0.0001）。CS的相关系数（r=0.86）低于CTC的相关系数（r=0.96）。内窥镜医师A和B的CS与病理之间的相关性分别为0.90和0.89。
结论：与CS相比，使用CTC测量的息肉大小更接近病理测量，表现出更大的变异性。这表明，如果患者同时接受CTC和结肠镜检查，则CTC可能更适合于临床环境中的息肉大小测量。
方法：分析包括在我们机构接受术前CTC的28例患者的61例结直肠息肉。所有息肉均经内镜切除。通过CS和CTC测量息肉大小。从两位内窥镜医师之一撰写的内窥镜检查记录中提取内窥镜息肉大小（A为11，B为6年内窥镜检查经验，分别)，谁在没有任何测量设备的情况下视觉/分类地估计尺寸。匹配位置后，在CTC上使用工作站上的手动三维(3D)测量息肉大小.病理检查后，还测量了切除的息肉的大小。CTC和组织学之间息肉大小的差异，使用配对t检验比较CS和组织学之间的差异。还分析了两位内窥镜医师之间的测量差异。
结果：使用CS测量的息肉的平均直径，反恐委员会，病理为10.5毫米，9.2mm,和8.4毫米，分别。CS与病理有显著的相关性，以及CTC和病理之间（均P<0.0001）。CS的相关系数（r=0.86）低于CTC的相关系数（r=0.96）。内窥镜医师A和B的CS与病理之间的相关性分别为0.90和0.89。
结论：与CS相比，使用CTC测量的息肉大小更接近病理测量，表现出更大的变异性。这表明，如果患者同时接受CTC和结肠镜检查，则CTC可能更适合于临床环境中的息肉大小测量。
