Abstract：
OBJECTIVE: Sinonasal tumors are a rare and heterogeneous group of malignant tumors with different histopathological characteristics and clinical presentation. These tumors are usually treated through surgery. The aim of this study is to present our results of surgical therapy in patients with an advanced sinonasal tumor.
METHODS: This retrospective study included patients with an advanced sinonasal tumor who were surgically treated. The surgical technique combined both a frontal transbasal approach together with an endoscopic endonasal approach. The parameters used for evaluation were the histological type of tumor, the radicality of resection (complete vs. incomplete), the frequency of recurrence, the surgical and postoperative complications, the type of subsequent oncological therapy and the overall survival.
RESULTS: The group consisted of ten patients seven were men and three were women. Complete resection (defined as R0) was achieved in 8 (80%) of the cases, subcomplete resection was achieved in 2 (20%) of the cases. The overall survival period was 28.7 months (95% confidence interval 15.9-41.6).
CONCLUSIONS: The combination of the frontal transbasal approach with the endoscopic endonasal approach is a suitable surgical strategy that enables easier achievement of complete tumor resection, reconstruction of the anterior skull base and reduces the need for extensive surgical approaches.
METHODS: This retrospective study included patients with an advanced sinonasal tumor who were surgically treated. The surgical technique combined both a frontal transbasal approach together with an endoscopic endonasal approach. The parameters used for evaluation were the histological type of tumor, the radicality of resection (complete vs. incomplete), the frequency of recurrence, the surgical and postoperative complications, the type of subsequent oncological therapy and the overall survival.
RESULTS: The group consisted of ten patients seven were men and three were women. Complete resection (defined as R0) was achieved in 8 (80%) of the cases, subcomplete resection was achieved in 2 (20%) of the cases. The overall survival period was 28.7 months (95% confidence interval 15.9-41.6).
CONCLUSIONS: The combination of the frontal transbasal approach with the endoscopic endonasal approach is a suitable surgical strategy that enables easier achievement of complete tumor resection, reconstruction of the anterior skull base and reduces the need for extensive surgical approaches.
摘要：
目的：鼻窦肿瘤是一类少见的异质性恶性肿瘤，具有不同的组织病理学特征和临床表现。这些肿瘤通常通过手术治疗。这项研究的目的是介绍我们对晚期鼻窦肿瘤患者的手术治疗结果。
方法：这项回顾性研究包括手术治疗的晚期鼻窦肿瘤患者。手术技术将额叶经基底入路与内窥镜鼻内入路相结合。用于评估的参数是肿瘤的组织学类型，切除的激进性(完整与不完整)，复发的频率，手术和术后并发症，后续肿瘤治疗的类型和总生存期。
结果：该组由10名患者组成，其中7名为男性，3名为女性。完全切除（定义为R0）在8例（80％）中实现，其中2例(20%)实现了不完全切除.总生存期为28.7个月（95％置信区间15.9-41.6）。
结论：经额基底入路与内镜经鼻入路的结合是一种合适的手术策略，可以更容易地实现肿瘤的完全切除。重建前颅底，减少了对广泛手术方法的需要。
方法：这项回顾性研究包括手术治疗的晚期鼻窦肿瘤患者。手术技术将额叶经基底入路与内窥镜鼻内入路相结合。用于评估的参数是肿瘤的组织学类型，切除的激进性(完整与不完整)，复发的频率，手术和术后并发症，后续肿瘤治疗的类型和总生存期。
结果：该组由10名患者组成，其中7名为男性，3名为女性。完全切除（定义为R0）在8例（80％）中实现，其中2例(20%)实现了不完全切除.总生存期为28.7个月（95％置信区间15.9-41.6）。
结论：经额基底入路与内镜经鼻入路的结合是一种合适的手术策略，可以更容易地实现肿瘤的完全切除。重建前颅底，减少了对广泛手术方法的需要。
