在心律失常性心肌病的临床前模型中 , NFB 信号通过 CCR2 + 巨噬细胞驱动心肌损伤。
Mesh : Animals Mice Signal Transduction Macrophages / metabolism pathology Receptors, CCR2 / metabolism genetics NF-kappa B / metabolism genetics Disease Models, Animal Myocardium / metabolism pathology Humans Arrhythmogenic Right Ventricular Dysplasia / genetics metabolism pathology Mice, Knockout
来 源:
DOI:10.1172/JCI183441
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