PDF(Pubmed)
Abstract：
UNASSIGNED: Gastrointestinal infections affect many people annually. The most common bacterial agents involved in these infections are enteropathogenic bacteria and in the continuation of using broad-spectrum antibiotics, Clostridium difficile-associated diarrhea is involved, especially in hospitalized patients. The aim of the present study was to investigate the pattern of antibiotic resistance among enteropathogenic bacteria.
UNASSIGNED: In this cross-sectional study, 163 samples of patients with diarrhea in Dezful Ganjavian Hospital were examined. The samples were cultured in MacConkey, Hektoen enteric agar and GN broth, and cycloserine cefoxitin fructose agar media and incubated under standard conditions. In order to identify enteropathogenic bacteria, biochemical tests and serological confirmatory tests were used. Antibiotic resistance pattern of the isolates was investigated by Kirby-Bauer disk diffusion susceptibility test.
UNASSIGNED: The frequency of pathogenic bacteria includes 41.1% of Shigella flexneri, followed by 41.1% of S. sonnei, 6.7% of Enteropathogenic E. coli, 5.5% of Salmonella enterica Serogroup B, and 5.5% of Shigella dysenteriae. The results revealed a total of 46 patients with orders regarding C. difficile culture, no C. difficile was isolated from the samples. The studied isolates showed the highest resistance to trimethoprim-sulfamethoxazole, and ceftriaxone (88.3%), and the most effective antibiotic in the treatment of patients was ciprofloxacin with 86% sensitivity.
UNASSIGNED: Susceptibility to antibiotics was different among the isolates, which shows that the early identification of the infection agent and the selection of the correct antibiotic treatment are effective in improving the gastrointestinal infection and preventing the spread of the infection.
UNASSIGNED: In this cross-sectional study, 163 samples of patients with diarrhea in Dezful Ganjavian Hospital were examined. The samples were cultured in MacConkey, Hektoen enteric agar and GN broth, and cycloserine cefoxitin fructose agar media and incubated under standard conditions. In order to identify enteropathogenic bacteria, biochemical tests and serological confirmatory tests were used. Antibiotic resistance pattern of the isolates was investigated by Kirby-Bauer disk diffusion susceptibility test.
UNASSIGNED: The frequency of pathogenic bacteria includes 41.1% of Shigella flexneri, followed by 41.1% of S. sonnei, 6.7% of Enteropathogenic E. coli, 5.5% of Salmonella enterica Serogroup B, and 5.5% of Shigella dysenteriae. The results revealed a total of 46 patients with orders regarding C. difficile culture, no C. difficile was isolated from the samples. The studied isolates showed the highest resistance to trimethoprim-sulfamethoxazole, and ceftriaxone (88.3%), and the most effective antibiotic in the treatment of patients was ciprofloxacin with 86% sensitivity.
UNASSIGNED: Susceptibility to antibiotics was different among the isolates, which shows that the early identification of the infection agent and the selection of the correct antibiotic treatment are effective in improving the gastrointestinal infection and preventing the spread of the infection.
摘要：
■胃肠道感染每年影响许多人。这些感染中最常见的细菌是肠道致病菌，并且在继续使用广谱抗生素时，涉及艰难梭菌相关性腹泻，尤其是住院患者。本研究的目的是研究肠致病菌对抗生素的耐药性。
■在这项横断面研究中，检查了DezfulGanjavian医院的163例腹泻患者样本。样品在MacConkey中培养,Hektoen肠琼脂和GN肉汤，和环丝氨酸头孢西丁果糖琼脂培养基，并在标准条件下孵育。为了鉴定肠道致病菌,使用生化试验和血清学确认试验。通过Kirby-Bauer纸片扩散敏感性试验研究了分离株的抗生素耐药性。
■病原菌的发生频率包括41.1%的福氏志贺氏菌，其次是S.sonnei的41.1％，6.7%的肠致病性大肠杆菌，5.5%的肠道沙门氏菌血清群B，和5.5%的痢疾志贺氏菌。结果显示，共有46例患者有关于艰难梭菌培养的医嘱，没有从样品中分离出艰难梭菌。研究的分离株对甲氧苄啶-磺胺甲恶唑的抗性最高，头孢曲松（88.3%），治疗患者最有效的抗生素是环丙沙星，其敏感性为86％。
■分离株对抗生素的敏感性不同，这表明，早期识别感染剂和选择正确的抗生素治疗对改善胃肠道感染和防止感染传播是有效的。
■在这项横断面研究中，检查了DezfulGanjavian医院的163例腹泻患者样本。样品在MacConkey中培养,Hektoen肠琼脂和GN肉汤，和环丝氨酸头孢西丁果糖琼脂培养基，并在标准条件下孵育。为了鉴定肠道致病菌,使用生化试验和血清学确认试验。通过Kirby-Bauer纸片扩散敏感性试验研究了分离株的抗生素耐药性。
■病原菌的发生频率包括41.1%的福氏志贺氏菌，其次是S.sonnei的41.1％，6.7%的肠致病性大肠杆菌，5.5%的肠道沙门氏菌血清群B，和5.5%的痢疾志贺氏菌。结果显示，共有46例患者有关于艰难梭菌培养的医嘱，没有从样品中分离出艰难梭菌。研究的分离株对甲氧苄啶-磺胺甲恶唑的抗性最高，头孢曲松（88.3%），治疗患者最有效的抗生素是环丙沙星，其敏感性为86％。
■分离株对抗生素的敏感性不同，这表明，早期识别感染剂和选择正确的抗生素治疗对改善胃肠道感染和防止感染传播是有效的。
