关键词: Anti-rabies serum rabies rabies vaccines re-exposure vaccine wastage

来  源:   DOI:10.4103/jfmpc.jfmpc_1612_23   PDF(Pubmed)

Abstract:
UNASSIGNED: Rabies has significant health and economic consequences for both humans and animals. Annually, India witnesses 17.4 million dog bites, yet only 3 million individuals receive post-exposure prophylaxis (PEP). There is a shortage of anti-rabies vaccine in India as quoted in many news reports. In India, lack of documentation of previous vaccination against animal bites is there, hence resulting in the re-administration of the anti-rabies vaccine, leading to a significant biological loss (anti-rabies vaccine).
UNASSIGNED: A cross-sectional, retrospective study was conducted. Data was collected, and analyzed from June 2021 to June 2023 a period of 2 years.
UNASSIGNED: Majority of the patients reported within the first 24 hours after being bitten while approximately one-third reported after 24 hours. Majority were Category 3 bites and unprovoked. Males, lower-middle class, and bites on lower extremities were common among 4291 patients attending the clinic. Out of 217 re-exposure cases, 185 did not have any documentation regarding their previous treatment of animal bites.
UNASSIGNED: Among 4291 patients attending the clinic, majority were Category 3 bites on the lower extremities. 85.25% of re-exposure cases had to be administered a full course of treatment due to a lack of documentation leading to rabies as a biological wastage. This avoidable wastage can be a resource for treating more patients.
摘要:
狂犬病对人类和动物都有重大的健康和经济后果。每年,印度见证了1740万只狗咬伤,然而,只有300万人接受暴露后预防(PEP)。正如许多新闻报道所引用的那样,印度的抗狂犬病疫苗短缺。在印度,缺乏以前针对动物咬伤的疫苗接种的文件,因此导致抗狂犬病疫苗的重新施用,导致显著的生物损失(抗狂犬病疫苗)。
横截面,进行了回顾性研究。收集数据,并分析了从2021年6月到2023年6月的2年时间。
大多数患者在被咬伤后的前24小时内报告,而大约三分之一在24小时后报告。大多数是第3类咬伤和无端咬伤。男性,中下阶层,在4291名患者中,下肢咬伤很常见。在217个再暴露病例中,185没有关于他们以前处理动物咬伤的任何文件。
在诊所就诊的4291名患者中,大多数是下肢的3类叮咬。85.25%的再暴露病例必须进行完整的治疗,因为缺乏文件会导致狂犬病作为生物浪费。这种可避免的浪费可以成为治疗更多患者的资源。
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