PDF(Pubmed)
Abstract：
Hepatitis E virus (HEV), responsible for widespread viral hepatitis, infects approximately 2.3 billion individuals globally, with a significant mortality burden in Asia. The virus, primarily transmitted through contaminated water and undercooked meat, is often underdiagnosed, particularly in immunocompromised patients. Current HEV treatments, while effective, are limited by adverse effects, necessitating research into safer alternatives. Moreover, HEV\'s extrahepatic manifestations, impacting the nervous and renal systems, remain poorly understood. This study underscores the imperative for enhanced HEV research, improved diagnostic methods, and more effective treatments, coupled with increased public health awareness and preventive strategies.
摘要：
戊型肝炎病毒(HEV),导致广泛的病毒性肝炎，感染全球约23亿人，在亚洲有很大的死亡负担。病毒,主要通过污染的水和未煮熟的肉传播，经常被诊断不足，特别是在免疫功能低下的患者中。目前的HEV治疗，虽然有效，受到不利影响的限制，需要研究更安全的替代品。此外，HEV的肝外表现，影响神经和肾脏系统，仍然知之甚少。这项研究强调了加强HEV研究的必要性，改进的诊断方法，和更有效的治疗方法，加上提高公众健康意识和预防策略。
