PDF(Pubmed)
Abstract：
Despite over 30 years of microbiome and skeletal muscle research, no quantitative analysis of sarcopenia and the microbiome literature had been conducted. Our bibliometric study examined research status, hotspots, and future trends. We utilized bibliometric techniques to search the Science Citation Index Extended Database on February 27, 2023, using the Bibliometrix package in R to create a map displaying scientific production and subject categories. Collaborative network maps between countries/regions were visualized using Scimago Graphica, while VOSviewer explored collaboration modes among individuals and institutions. We analyzed the top 25 emerging keywords, top co-occurring keyword networks, and co-occurring keyword clusters using CiteSpace. A total of 997 articles were retrieved for sarcopenia and microbiome, of which 633 papers were analyzed. Both the number of publications and total citation frequency had been continuously increasing. The United States had the highest total citation frequency, while China had the highest number of publications. Research on the impact of the microbiome on sarcopenia was in its nascent stage and spans multiple disciplines, including nutrition, microbiology, geriatrics, immunology, endocrinology and metabolism, molecular biology, and sports medicine. The University of Copenhagen contributed the most to the number of publications (n=16), with Tibbett M (n=7) and Hulver MW (n=7) among the top authors. The most published journal was \"Nutrients\" (n=24). Analysis of keywords and clusters revealed new research hotspots in microbes and sarcopenia, such as malnutrition, dietary fiber, signaling pathways, frailty, and intestinal permeability. Research on the impact of the microbiome on sarcopenia is in its infancy and spans multiple disciplines. Malnutrition, dietary fiber, signaling pathways, frailty, and intestinal microbes are currently research hotspots. Furthermore, the visual atlas analysis of research on microbes and sarcopenia helps to track the knowledge structure in research fields related to sarcopenia and microbes, providing direction for future research.
摘要：
尽管有30多年的微生物组和骨骼肌研究，没有对肌肉减少症和微生物组文献进行定量分析.我们的文献计量学研究考察了研究现状，热点,和未来趋势。我们利用文献计量技术在2023年2月27日搜索科学引文索引扩展数据库，使用R中的Bibliometrix包创建显示科学生产和主题类别的地图。使用ScimagoGraphica可视化了国家/地区之间的协作网络地图，而VOSviewer探索了个人和机构之间的协作模式。我们分析了前25个新兴关键词，顶级共同出现的关键词网络，和使用CiteSpace共同出现的关键字集群。共检索到997篇关于肌肉减少症和微生物组的文章，其中633篇论文进行了分析。出版物数量和总引用频率都在不断增加。美国的总引用频率最高，而中国的出版物数量最多。微生物群对肌肉减少症的影响研究处于起步阶段，跨越多个学科，包括营养,微生物学,老年病学,免疫学,内分泌学和新陈代谢，分子生物学,和运动医学。哥本哈根大学对出版物的数量贡献最大（n=16），TibbettM（n=7）和HulverMW（n=7）是顶级作者。发表最多的期刊是“营养素”（n=24）。关键词和聚类分析揭示了微生物和肌少症的新研究热点，比如营养不良，膳食纤维，信号通路，脆弱,和肠道通透性。关于微生物群对肌肉减少症的影响的研究处于起步阶段，跨越多个学科。营养不良,膳食纤维，信号通路，脆弱,和肠道微生物是目前的研究热点。此外，微生物和少肌症研究的可视化图谱分析有助于追踪少肌症和微生物相关研究领域的知识结构,为今后的研究提供方向。
