PDF(Pubmed)
Abstract：
UNASSIGNED: Obesity disproportionately affects marginalized and low-income populations. Birth parent obesity from the prenatal period and childhood has been associated with child obesity. It is unknown whether prenatal or postnatal birth parent obesity has differential effects on subsequent changes in adiposity and metabolic health in children.
UNASSIGNED: We evaluated how birth parent obesity 7 y after delivery was associated with child body composition changes and cardiometabolic health in midchildhood and further assessed the influence of the perinatal and postpartum period on associations.
UNASSIGNED: Black and Dominican pregnant individuals were enrolled, and dyads (n = 319) were followed up at child age 7 and 9 y. Measures included, height, weight, waist circumference (WC), and percent body fat (BF%). Multiple linear regression was used to relate postpartum weight status with child outcomes accounting for attrition, and a series of secondary analyses were conducted with additional adjustment for perinatal weight status, gestational weight gain (GWG), and/or long-term weight retention to evaluate how these factors influenced associations.
UNASSIGNED: Almost one-quarter (23%) of birth parents and 24.1% children were classified with obesity at child age 7 y, while at 9 y, 30% of children had obesity. Birth parent obesity at child age 7 y was associated with greater changes, from ages 7 to 9 y, in child BMI z-score (β: 0.13; 95% CI: 0.02, 0.24) and BF% (β: 1.15; 95% CI: 0.22, 2.09) but not obesity at age 9 y. All observed associations crossed the null after additional adjustment for prenatal factors.
UNASSIGNED: Birth parent obesity at 7-y postpartum is associated with greater gains in child BMI z-score and BF% in midchildhood. These associations diminish after accounting for prenatal size, suggesting a lasting impact of the perinatal environment and that interventions supporting families from the prenatal period through childhood are needed.
UNASSIGNED: We evaluated how birth parent obesity 7 y after delivery was associated with child body composition changes and cardiometabolic health in midchildhood and further assessed the influence of the perinatal and postpartum period on associations.
UNASSIGNED: Black and Dominican pregnant individuals were enrolled, and dyads (n = 319) were followed up at child age 7 and 9 y. Measures included, height, weight, waist circumference (WC), and percent body fat (BF%). Multiple linear regression was used to relate postpartum weight status with child outcomes accounting for attrition, and a series of secondary analyses were conducted with additional adjustment for perinatal weight status, gestational weight gain (GWG), and/or long-term weight retention to evaluate how these factors influenced associations.
UNASSIGNED: Almost one-quarter (23%) of birth parents and 24.1% children were classified with obesity at child age 7 y, while at 9 y, 30% of children had obesity. Birth parent obesity at child age 7 y was associated with greater changes, from ages 7 to 9 y, in child BMI z-score (β: 0.13; 95% CI: 0.02, 0.24) and BF% (β: 1.15; 95% CI: 0.22, 2.09) but not obesity at age 9 y. All observed associations crossed the null after additional adjustment for prenatal factors.
UNASSIGNED: Birth parent obesity at 7-y postpartum is associated with greater gains in child BMI z-score and BF% in midchildhood. These associations diminish after accounting for prenatal size, suggesting a lasting impact of the perinatal environment and that interventions supporting families from the prenatal period through childhood are needed.
摘要：
■肥胖不成比例地影响边缘化和低收入人群。出生父母肥胖从产前和儿童期一直与儿童肥胖有关。尚不清楚出生前或出生后的父母肥胖是否会对随后的儿童肥胖和代谢健康变化产生不同的影响。
我们评估了分娩后7年出生父母肥胖与儿童中期身体成分变化和心脏代谢健康的关系，并进一步评估了围产期和产后对这种关系的影响。
■黑人和多米尼加孕妇参加了研究，并在7岁和9岁的儿童进行了随访（n=319）。措施包括，高度,体重,腰围（WC），和身体脂肪百分比(BF%)。使用多元线性回归将产后体重状况与儿童结局联系起来，并进行了一系列二次分析，并对围产期体重状况进行了额外的调整，妊娠期体重增加（GWG），和/或长期体重保持率，以评估这些因素如何影响关联。
近四分之一（23%）的亲生父母和24.1%的儿童在7岁时被归类为肥胖，而在9岁时，30%的儿童患有肥胖症。7岁儿童出生时父母肥胖与更大的变化相关，从7岁到9岁，儿童BMIz评分(β:0.13;95%CI:0.02,0.24)和BF%(β:1.15;95%CI:0.22,2.09),但不包括9岁时的肥胖。在对产前因素进行额外调整后,所有观察到的关联均为零。
产后7岁时出生父母肥胖与儿童BMIz评分和儿童期BF%的增加有关。考虑到产前大小后，这些关联会减弱，提示围产期环境的持久影响，并且需要从产前到儿童期支持家庭的干预措施。
我们评估了分娩后7年出生父母肥胖与儿童中期身体成分变化和心脏代谢健康的关系，并进一步评估了围产期和产后对这种关系的影响。
■黑人和多米尼加孕妇参加了研究，并在7岁和9岁的儿童进行了随访（n=319）。措施包括，高度,体重,腰围（WC），和身体脂肪百分比(BF%)。使用多元线性回归将产后体重状况与儿童结局联系起来，并进行了一系列二次分析，并对围产期体重状况进行了额外的调整，妊娠期体重增加（GWG），和/或长期体重保持率，以评估这些因素如何影响关联。
近四分之一（23%）的亲生父母和24.1%的儿童在7岁时被归类为肥胖，而在9岁时，30%的儿童患有肥胖症。7岁儿童出生时父母肥胖与更大的变化相关，从7岁到9岁，儿童BMIz评分(β:0.13;95%CI:0.02,0.24)和BF%(β:1.15;95%CI:0.22,2.09),但不包括9岁时的肥胖。在对产前因素进行额外调整后,所有观察到的关联均为零。
产后7岁时出生父母肥胖与儿童BMIz评分和儿童期BF%的增加有关。考虑到产前大小后，这些关联会减弱，提示围产期环境的持久影响，并且需要从产前到儿童期支持家庭的干预措施。
