Abstract:
Histoplasma capsulatum is a dimorphic fungus that grows in nature as a mold or in culture but converts to a small yeast during cellular invasion. While most histoplasmosis infections are primarily asymptomatic or mildly symptomatic, disseminated histoplasmosis is a relentlessly progressive granulomatous disease that can mimic other granulomatous diseases, such as tuberculosis, sarcoidosis or coccidioidomycosis, more so in the proper context of immunosuppression. The current global migrant crisis, particularly the United States migrant crisis conversation is mostly socio-political; however, it also has a public health implication as exemplified by the case of a 35-year-old male who migrated from Haiti via Chile and Mexico to the United States. He presented with a four-day history of fever, generalized body aches, and cough. This case underscores the importance of entertaining a myriad of differentials and avoiding the tendency for anchoring, especially when initial therapy yields little clinical response.
摘要:
荚膜组织支原体是一种双态真菌,在自然界中作为霉菌或培养物生长,但在细胞入侵期间转化为小酵母。虽然大多数组织胞浆菌病感染主要是无症状或轻度症状,播散性组织胞浆菌病是一种无情地进行性肉芽肿疾病,可以模仿其他肉芽肿疾病,如肺结核,结节病或球孢子菌病,在免疫抑制的适当背景下更是如此。当前的全球移民危机,特别是美国移民危机的对话大多是社会政治的;然而,它还具有公共卫生意义,例如一名35岁的男性从海地经智利和墨西哥移民到美国。他有四天的发烧史,全身疼痛,还有咳嗽.这个案例强调了娱乐无数差异和避免锚定趋势的重要性,特别是当初始治疗产生很少的临床反应。