PDF(Pubmed)
Abstract：
The papillary tumor of the pineal region (PTPR) is a rare neuroepithelial tumor originating from specialized ependymocytes. It primarily affects structures within the pineal region, including the pineal gland, epithalamus, quadrigeminal cistern, and posterior wall of the third ventricle. Here, we present a series of four cases characterized by symptoms associated with obstructive hydrocephalus such as headaches, seizures, visual disturbances, gait disturbances, and Parinaud syndrome. Imaging studies revealed lesions in the pineal region, prompting surgical intervention. Histopathological examination, including biopsy and intraoperative analysis, confirmed the diagnosis of PTPR. Despite advancements, the etiology and pathogenesis of PTPR remain incompletely understood, warranting further research to refine management strategies.
摘要：
松果体区乳头状肿瘤（PTPR）是一种罕见的神经上皮肿瘤，起源于特化的室管膜细胞。它主要影响松果体区域内的结构，包括松果体,上丘脑,四叉池,和第三脑室的后壁。这里,我们介绍了一系列四例病例，其特征是与阻塞性脑积水相关的症状，如头痛，癫痫发作,视觉障碍,步态紊乱,和Parinaud综合征.影像学检查显示松果体区有病变,提示手术干预。组织病理学检查，包括活检和术中分析,证实了PTPR的诊断。尽管取得了进步，PTPR的病因和发病机制尚不完全清楚，保证进一步研究以完善管理策略。
