关键词: AIDS defining malignancy HAART HIV Kaposi sarcoma RVI

来  源:   DOI:10.1016/j.idcr.2024.e02003   PDF(Pubmed)

Abstract:
Kaposi sarcoma is an indolent angio-proliferative spindle- cell tumor derived from endothelial and immune cells infected with Human herpes virus type 8(HHV-8). In the era of highly active antiretroviral (HAART), Kaposi sarcoma is a rare form of initial presentation of HIV infection [1]. The author presents a case of diffuse gingival hypertrophied Kaposi sarcoma in 18-year-old male newly diagnosed RVI patient. After confirming the diagnosis patient started on HAART and mouth care. Surgical excision is the first line of treatment with HAART, since this patient has low CD4 count of 30 cells/mm3 which will complicate the surgery. So, we are waiting for CD4 count to increase above 200 cells/mm3 to undergo surgical excision. The case is representative of HIV complexity and aimed to bring awareness of unusual presentation of HIV.This case also reminds us how important early initiation of HAART is.
摘要:
卡波西肉瘤是一种惰性血管增殖性纺细胞肿瘤,来源于感染人疱疹病毒8型(HHV-8)的内皮细胞和免疫细胞。在高活性抗逆转录病毒(HAART)时代,卡波西肉瘤是最初表现为HIV感染的一种罕见形式[1]。作者介绍了一例18岁男性新诊断的RVI患者的弥漫性牙龈肥大性卡波西肉瘤。确认诊断后,患者开始接受HAART和口腔护理。手术切除是HAART治疗的第一线,因为该患者的CD4计数低,为30个细胞/mm3,这将使手术复杂化。所以,我们正在等待CD4计数增加到200细胞/mm3以上进行手术切除。该案例代表了艾滋病毒的复杂性,旨在提高人们对艾滋病毒异常表现的认识。这个案例也提醒我们早期开始HAART是多么重要。
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