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Abstract：
UNASSIGNED: To analyze the effectiveness of the \"Xinjiang Model\" for tuberculosis prevention and control in Kashgar Prefecture, Xinjiang, and to explore the determinants of the policy implementation effect.
UNASSIGNED: The registration data of pulmonary tuberculosis (PTB) patients in Kashgar Prefecture from 2012 to 2021 were collected to describe the temporal trend of registered incidence. A questionnaire survey was conducted among PTB patients registered and treated in the tuberculosis management information system in Zepu and Shache Counties from January 2022 to July 2023 to collect and analyze \"Xinjiang model\" determinants of effectiveness.
UNASSIGNED: The PTB registered incidence in Kashgar Prefecture showed a significant increasing trend from 2012 to 2018 (APC=18.7%) and a significant decreasing trend from 2018-2021 (APC=-28.8%). Among the Kashgar Prefecture, compared with average registered incidence in 2012-2017, registered incidence in 2021 in Shufu, Maigaiti, and Zepu Counties had a greater decline rate of 58.68%, 57.16%, and 54.02%, respectively, while the registered incidence in 2021 in Shache County increased by 6.32%. According to the comprehensive analysis of the factors affecting the effect of policy implementation, the proportion of PTB patients in Zepu County whose health status has now significantly improved compared with that before treatment was significantly greater than that in Shache County (P<0.05); patients in Shache County were significantly less aware than those in Zepu County of how to take tuberculosis drugs, precautions, adverse reactions, and regular reviews during treatment; the factors that accounted for the greater proportion of heavy treatment burden in both Shache and Zepu Counties were discomfort caused by taking or injecting drugs, accounting for 12.8% and 8.7%, respectively.
UNASSIGNED: The \"Xinjiang model\" can effectively control the epidemic situation of tuberculosis in Kashgar, and the knowledge of tuberculosis treatment, adverse reactions to tuberculosis drugs, and treatment costs were the determinants of the effectiveness of policy implementation.
UNASSIGNED: The registration data of pulmonary tuberculosis (PTB) patients in Kashgar Prefecture from 2012 to 2021 were collected to describe the temporal trend of registered incidence. A questionnaire survey was conducted among PTB patients registered and treated in the tuberculosis management information system in Zepu and Shache Counties from January 2022 to July 2023 to collect and analyze \"Xinjiang model\" determinants of effectiveness.
UNASSIGNED: The PTB registered incidence in Kashgar Prefecture showed a significant increasing trend from 2012 to 2018 (APC=18.7%) and a significant decreasing trend from 2018-2021 (APC=-28.8%). Among the Kashgar Prefecture, compared with average registered incidence in 2012-2017, registered incidence in 2021 in Shufu, Maigaiti, and Zepu Counties had a greater decline rate of 58.68%, 57.16%, and 54.02%, respectively, while the registered incidence in 2021 in Shache County increased by 6.32%. According to the comprehensive analysis of the factors affecting the effect of policy implementation, the proportion of PTB patients in Zepu County whose health status has now significantly improved compared with that before treatment was significantly greater than that in Shache County (P<0.05); patients in Shache County were significantly less aware than those in Zepu County of how to take tuberculosis drugs, precautions, adverse reactions, and regular reviews during treatment; the factors that accounted for the greater proportion of heavy treatment burden in both Shache and Zepu Counties were discomfort caused by taking or injecting drugs, accounting for 12.8% and 8.7%, respectively.
UNASSIGNED: The \"Xinjiang model\" can effectively control the epidemic situation of tuberculosis in Kashgar, and the knowledge of tuberculosis treatment, adverse reactions to tuberculosis drugs, and treatment costs were the determinants of the effectiveness of policy implementation.
摘要：
■分析喀什地区结核病防治“新疆模式”的有效性，新疆,并探讨政策实施效果的决定因素。
■收集了2012-2021年喀什地区肺结核（PTB）患者的登记数据，以描述登记发病率的时间趋势。对2022年1月至2023年7月在泽普县和莎车县结核病管理信息系统中登记和治疗的PTB患者进行问卷调查，以收集和分析“新疆模式”的有效性决定因素。
■2012-2018年喀什地区PTB登记发病率呈显著上升趋势（APC=18.7%），2018-2021年呈显著下降趋势（APC=-28.8%）。在喀什地区,与2012-2017年的平均登记发病率相比，2021年舒福市的登记发病率，Maigaiti,泽普县下降幅度更大，达到58.68%，57.16%,和54.02%，分别,而2021年莎车县的登记发病率增加了6.32%。根据对影响政策实施效果的因素的综合分析,泽普县目前健康状况较治疗前明显改善的肺结核患者比例明显高于莎车县（P<0.05）；莎车县患者对如何服用抗结核药物的知晓率明显低于泽普县，预防措施,不良反应,并在治疗期间定期复查;在莎车县和泽普县均占较重治疗负担比例较大的因素是服用或注射药物引起的不适,占12.8%和8.7%，分别。
■"新疆模式"能有效控制喀什地区结核病疫情,以及结核病治疗的知识，结核病药物的不良反应，治疗费用是政策执行效果的决定因素。
■收集了2012-2021年喀什地区肺结核（PTB）患者的登记数据，以描述登记发病率的时间趋势。对2022年1月至2023年7月在泽普县和莎车县结核病管理信息系统中登记和治疗的PTB患者进行问卷调查，以收集和分析“新疆模式”的有效性决定因素。
■2012-2018年喀什地区PTB登记发病率呈显著上升趋势（APC=18.7%），2018-2021年呈显著下降趋势（APC=-28.8%）。在喀什地区,与2012-2017年的平均登记发病率相比，2021年舒福市的登记发病率，Maigaiti,泽普县下降幅度更大，达到58.68%，57.16%,和54.02%，分别,而2021年莎车县的登记发病率增加了6.32%。根据对影响政策实施效果的因素的综合分析,泽普县目前健康状况较治疗前明显改善的肺结核患者比例明显高于莎车县（P<0.05）；莎车县患者对如何服用抗结核药物的知晓率明显低于泽普县，预防措施,不良反应,并在治疗期间定期复查;在莎车县和泽普县均占较重治疗负担比例较大的因素是服用或注射药物引起的不适,占12.8%和8.7%，分别。
■"新疆模式"能有效控制喀什地区结核病疫情,以及结核病治疗的知识，结核病药物的不良反应，治疗费用是政策执行效果的决定因素。
