PDF(Pubmed)
Abstract：
The exploration of newer antibacterial strategies is driven by antibiotic-resistant microbes that cause serious public health issues. In recent years, nanoscale materials have developed as an alternative method to fight infections. Despite the fact that many nanomaterials have been discovered to be harmful, numerous researchers have shown a keen interest in nanoparticles (NPs) made of noble metals like silver, gold and platinum. To make environmentally safe NPs from plants, green chemistry and nanotechnology have been combined to address the issue of toxicity. The study of bimetallic nanoparticles (BNPs) has increased tremendously in the past 10 years. The production of BNPs mediated by natural extracts is straightforward, low cost and environmentally friendly. Due to their low toxicity, safety and biological stability, noble BNPs with silver, gold, platinum and palladium have the potential to be used in biomedical applications. They have a significant impact on human health and are used in medicine and pharmacy due to their biological characteristics, which include catalytic, antioxidant, antibacterial, antidiabetic, anticancer, hepatoprotective and regenerative activity.
摘要：
新的抗菌策略的探索是由引起严重公共卫生问题的抗生素抗性微生物推动的。近年来,纳米级材料已经发展成为对抗感染的替代方法。尽管许多纳米材料被发现是有害的，许多研究人员对由银等贵金属制成的纳米颗粒（NPs）表现出浓厚的兴趣，黄金和铂金。为了从植物中制造环境安全的NP，绿色化学和纳米技术结合起来解决了毒性问题。在过去的10年中，双金属纳米粒子（BNPs）的研究得到了极大的发展。由天然提取物介导的BNP的产生是简单的，低成本和环保。由于其低毒性,安全性和生物稳定性，高贵的BNP与银，黄金,铂和钯具有用于生物医学应用的潜力。它们对人类健康有重大影响，由于其生物学特性而被用于医学和药学，其中包括催化，抗氧化剂，抗菌，抗糖尿病药,抗癌，保肝和再生活性。
