PDF(Pubmed)
Abstract：
UNASSIGNED: Bilothorax is defined as the presence of bile in the pleural space. It is a rare condition, and diagnosis is confirmed with a pleural fluid-to-serum bilirubin ratio of >1.
UNASSIGNED: The PubMed, Embase, Google Scholar, and CINAHL databases were searched using predetermined Boolean parameters. The systematic literature review was done per PRISMA guidelines. Retrospective studies, case series, case reports, and conference abstracts were included. The patients with reported pleural fluid analyses were pooled for fluid parameter data analysis.
UNASSIGNED: Of 838 articles identified through the inclusion criteria and removing 105 duplicates, 732 articles were screened with abstracts, and 285 were screened for full article review. After this, 123 studies qualified for further detailed review, and of these, 115 were pooled for data analysis. The mean pleural fluid and serum bilirubin levels were 72 mg/dL and 61 mg/dL, respectively, with a mean pleural fluid-to-serum bilirubin ratio of 3.47. In most cases, the bilothorax was reported as a subacute or remote complication of hepatobiliary surgery or procedure, and traumatic injury to the chest or abdomen was the second most common cause. Tube thoracostomy was the main treatment modality (73.83%), followed by serial thoracentesis. Fifty-two patients (51.30%) had associated bronchopleural fistulas. The mortality was considerable, with 18/115 (15.65%) reported death. Most of the patients with mortality had advanced hepatobiliary cancer and were noted to die of complications not related to bilothorax.
UNASSIGNED: Bilothorax should be suspected in patients presenting with pleural effusion following surgical manipulation of hepatobiliary structures or a traumatic injury to the chest. This review is registered with CRD42023438426.
UNASSIGNED: The PubMed, Embase, Google Scholar, and CINAHL databases were searched using predetermined Boolean parameters. The systematic literature review was done per PRISMA guidelines. Retrospective studies, case series, case reports, and conference abstracts were included. The patients with reported pleural fluid analyses were pooled for fluid parameter data analysis.
UNASSIGNED: Of 838 articles identified through the inclusion criteria and removing 105 duplicates, 732 articles were screened with abstracts, and 285 were screened for full article review. After this, 123 studies qualified for further detailed review, and of these, 115 were pooled for data analysis. The mean pleural fluid and serum bilirubin levels were 72 mg/dL and 61 mg/dL, respectively, with a mean pleural fluid-to-serum bilirubin ratio of 3.47. In most cases, the bilothorax was reported as a subacute or remote complication of hepatobiliary surgery or procedure, and traumatic injury to the chest or abdomen was the second most common cause. Tube thoracostomy was the main treatment modality (73.83%), followed by serial thoracentesis. Fifty-two patients (51.30%) had associated bronchopleural fistulas. The mortality was considerable, with 18/115 (15.65%) reported death. Most of the patients with mortality had advanced hepatobiliary cancer and were noted to die of complications not related to bilothorax.
UNASSIGNED: Bilothorax should be suspected in patients presenting with pleural effusion following surgical manipulation of hepatobiliary structures or a traumatic injury to the chest. This review is registered with CRD42023438426.
摘要：
■Bilothorax定义为胸膜腔中胆汁的存在。这是一种罕见的情况，胸膜液与血清胆红素比值>1时确诊。
■PubMed，Embase,谷歌学者，使用预定的布尔参数搜索和CINAHL数据库。根据PRISMA指南进行系统文献综述。回顾性研究,案例系列,病例报告,包括会议摘要。合并报告有胸腔积液分析的患者，以进行流体参数数据分析。
■在通过纳入标准确定的838篇文章中，删除了105篇重复文章，732篇文章用摘要进行了筛选，对285例进行了全面审查。在这之后,123项研究有资格进行进一步的详细审查，其中，将115个数据汇总用于数据分析。平均胸水和血清胆红素水平为72mg/dL和61mg/dL，分别,平均胸水与血清胆红素的比值为3.47。在大多数情况下,据报道，胆胸是肝胆手术或手术的亚急性或远端并发症，胸部或腹部的外伤是第二大常见原因。管状胸腔造口术是主要的治疗方式(73.83%)，然后是连续胸腔穿刺术.52例患者（51.30％）患有相关的支气管胸膜瘘。死亡率相当高，18/115（15.65%）报告死亡。大多数死亡患者患有晚期肝胆管癌，并死于与胆胸无关的并发症。
■在手术操作肝胆结构或胸部外伤后出现胸腔积液的患者应怀疑有Bilothorax。此评论已在CRD42023438426注册。
■PubMed，Embase,谷歌学者，使用预定的布尔参数搜索和CINAHL数据库。根据PRISMA指南进行系统文献综述。回顾性研究,案例系列,病例报告,包括会议摘要。合并报告有胸腔积液分析的患者，以进行流体参数数据分析。
■在通过纳入标准确定的838篇文章中，删除了105篇重复文章，732篇文章用摘要进行了筛选，对285例进行了全面审查。在这之后,123项研究有资格进行进一步的详细审查，其中，将115个数据汇总用于数据分析。平均胸水和血清胆红素水平为72mg/dL和61mg/dL，分别,平均胸水与血清胆红素的比值为3.47。在大多数情况下,据报道，胆胸是肝胆手术或手术的亚急性或远端并发症，胸部或腹部的外伤是第二大常见原因。管状胸腔造口术是主要的治疗方式(73.83%)，然后是连续胸腔穿刺术.52例患者（51.30％）患有相关的支气管胸膜瘘。死亡率相当高，18/115（15.65%）报告死亡。大多数死亡患者患有晚期肝胆管癌，并死于与胆胸无关的并发症。
■在手术操作肝胆结构或胸部外伤后出现胸腔积液的患者应怀疑有Bilothorax。此评论已在CRD42023438426注册。
