UNASSIGNED: Ross 308 broilers were grouped into three experimental and one control group. Doxycycline was administered in drinking water at therapeutic and sub-therapeutic doses, as well as via spray treatment. The concentration of doxycycline in bones was determined post slaughter by ultra-high performance liquid chromatography-tandem mass spectrometry.
UNASSIGNED: Doxycycline was quantified at 135 μg/kg 22 days after the last day of antibiotic administration at therapeutic doses; 2,285 μg/kg after sub-therapeutic treatment for 27 days and 9.62 μg/kg 22 days after the end of spray application.
UNASSIGNED: High concentrations and long persistence of doxycycline in bones were found in this study. Doxycycline can contaminate all bone-derived products in the food and fertiliser industries.
■Ross308肉鸡分为三个实验组和一个对照组。多西环素在饮用水中以治疗剂量和亚治疗剂量给药,以及通过喷雾处理。用超高效液相色谱-串联质谱法测定屠宰后骨骼中多西环素的浓度。
强力霉素在治疗剂量抗生素给药最后一天后22天定量为135μg/kg;亚治疗治疗27天后为2,285μg/kg,喷雾结束后22天9.62μg/kg。
■在这项研究中发现了强力霉素在骨骼中的高浓度和长期持久性。强力霉素会污染食品和化肥行业中的所有骨骼衍生产品。