关键词: advanced age autoimmune disease diagnosis late-onset systemic lupus erythematosus pleural effusion systemic lupus erythematosus disease

来  源:   DOI:10.7759/cureus.63327   PDF(Pubmed)

Abstract:
Systemic lupus erythematosus (SLE) is a chronic, multisystem autoimmune disease that can manifest in older individuals, presenting unique diagnostic challenges because of its atypical presentations and comorbidities. Pleural effusion is a relatively uncommon manifestation of SLE, with studies suggesting a higher prevalence in older than younger patients. We herein report an atypical case of delayed-onset SLE in a 75-year-old man with left-sided pleural effusion as the initial presentation. This case underscores the difficulty of diagnosing SLE in patients of advanced age and the importance of considering a broad range of differential diagnoses, even in cases that may suggest a more common disease. This case also highlights the fact that unilateral pleural effusion can be an initial manifestation of SLE, and when the cause of the pleural effusion is unclear, SLE should be considered as a potential diagnosis.
摘要:
系统性红斑狼疮(SLE)是一种慢性,多系统自身免疫性疾病,可以在老年人身上表现出来,由于其非典型表现和合并症,提出了独特的诊断挑战。胸腔积液是SLE的一种相对少见的表现,研究表明,老年患者的患病率高于年轻患者。我们在此报告了一名75岁男性的典型延迟性SLE病例,该病例以左侧胸腔积液为首发表现。该病例强调了高龄患者诊断SLE的难度以及考虑广泛鉴别诊断的重要性。即使在可能暗示更常见的疾病的情况下。该病例还强调了一个事实,即单侧胸腔积液可以是SLE的初始表现,当胸腔积液的原因不清楚时,SLE应被视为潜在的诊断。
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