PDF(Pubmed)
Abstract：
Silkworm (Bombyx mori) larvae are expected to be useful as an ingredient in entomophagy. They are full of nutrients, including indigestible proteins; however, there have been few studies on the effects of the consumption of the entire body of silkworms on the intestinal microflora. We prepared a customized diet containing silkworm larval powder (SLP), and investigated the effects of ad libitum feeding of the SLP diet on the intestinal microbiota and the amount of short-chain fatty acids (SCFAs) in mice. We found that the diversity of the cecal and fecal microbiota increased in the mice fed the SLP diet (SLP group), and that the composition of their intestinal microbiota differed from that of the control mice. Furthermore, a genus-level microbiota analysis showed that in the SLP group, the proportions of Alistipes, Lachnospiraceae A2, and RF39, which are associated with the prevention of obesity, were significantly increased, while the proportions of Helicobacter and Anaerotruncus, which are associated with obesity, were significantly decreased. Additionally, the level of butyrate was increased in the SLP group, and Clostridia UCG 014 and Lachnospiraceae FCS020 were found to be associated with the level of butyrate, one of the major SCFAs. These findings indicated that silkworm powder may be useful as an insect food that might also improve obesity.
摘要：
家蚕（Bombyxmori）幼虫有望用作昆虫吞噬的成分。它们充满了营养，包括不可消化的蛋白质；然而，关于食用整个家蚕对肠道菌群的影响的研究很少。我们准备了含有家蚕幼虫粉（SLP）的定制饮食，并研究了随意饲喂SLP饮食对小鼠肠道菌群和短链脂肪酸（SCFA）含量的影响。我们发现，饲喂SLP饮食（SLP组）的小鼠盲肠和粪便微生物群的多样性增加，它们的肠道微生物群的组成与对照小鼠的不同。此外，属水平的微生物群分析表明，在SLP组中，Alistipes的比例，LachnoshileaeA2和RF39，与预防肥胖有关，显着增加，而螺杆菌和厌氧菌的比例，与肥胖有关，显着下降。此外,SLP组丁酸水平升高,和梭菌UCG014和LachnospiphaceaeFCS020被发现与丁酸的水平有关，主要的SCFA之一。这些发现表明，蚕粉可以用作昆虫食品，也可以改善肥胖。
