PDF(Pubmed)
Abstract：
The Baveno VII criteria redefine the management of decompensated liver cirrhosis, introducing the concept of hepatic recompensation marking a significant departure from the conventional view of irreversible decline. Central to this concept is addressing the underlying cause of cirrhosis through tailored therapies, including antivirals and lifestyle modifications. Studies on alcohol, hepatitis C virus, and hepatitis B virus-related cirrhosis demonstrate the efficacy of these interventions in improving liver function and patient outcomes. Transjugular intrahepatic portosystemic shunt (TIPS) emerges as a promising intervention, effectively resolving complications of portal hypertension and facilitating recompensation. However, optimal timing and patient selection for TIPS remain unresolved. Despite challenges, TIPS offers renewed hope for hepatic recompensation, marking a significant advancement in cirrhosis management. Further research is needed to refine its implementation and maximize its benefits. In conclusion, TIPS stands as a promising avenue for improving hepatic function and patient outcomes in decompensated liver cirrhosis within the framework of the Baveno VII criteria.
摘要：
BavenoVII标准重新定义了失代偿期肝硬化的管理，引入肝脏再补偿的概念标志着与传统的不可逆转的观点大相径庭。这个概念的核心是通过量身定制的疗法解决肝硬化的根本原因，包括抗病毒药物和生活方式的改变。关于酒精的研究,丙型肝炎病毒，和乙型肝炎病毒相关性肝硬化证明了这些干预措施在改善肝功能和患者预后方面的有效性。经颈静脉肝内门体分流术（TIPS）是一种有希望的干预措施，有效解决门静脉高压症并发症，促进再补偿。然而,TIPS的最佳时机和患者选择仍未解决。尽管面临挑战,TIPS为肝脏恢复提供了新的希望，标志着肝硬化管理的显著进步。需要进一步的研究来完善其实施并最大化其利益。总之,TIPS是在BavenoVII标准框架内改善失代偿期肝硬化的肝功能和患者预后的有希望的途径。
