关键词: activity biomarker diet lifestyle interventions metabolic dysfunction-associated fatty liver disease

来  源:   DOI:10.3389/fnut.2024.1424246   PDF(Pubmed)

Abstract:
MAFLD has become a major global health problem and is the leading cause of liver disease worldwide. The disease progresses from a simple fatty liver to gradual fibrosis, which progresses to cirrhosis and even hepatocellular liver cancer. However, the methods currently used for diagnosis are invasive and do not facilitate clinical assessment of the condition. As a result, research on markers for the diagnosis of MAFLD is increasing. In addition, there are no clinical medications for the treatment of MAFLD, and lifestyle interventions remain effective in the prevention and treatment of MAFLD. In this review, we attempt to make a summary of the emerging diagnostic indicators and effective lifestyle interventions for MAFLD and to provide new insights into the diagnosis and treatment of MAFLD.
摘要:
MAFLD已成为全球主要的健康问题,是全球肝病的主要原因。这种疾病从单纯的脂肪肝发展到逐渐的纤维化,进展为肝硬化,甚至肝细胞肝癌。然而,目前用于诊断的方法是侵入性的,不利于病情的临床评估。因此,对MAFLD诊断标志物的研究日益增多。此外,没有临床药物治疗MAFLD,生活方式干预在MAFLD的预防和治疗中仍然有效。在这次审查中,我们试图总结MAFLD的新兴诊断指标和有效的生活方式干预措施,并为MAFLD的诊断和治疗提供新的见解.
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