关键词: Arbovirus Domestic animals Neutralizing antibodies One health Serosurvey

来  源:   DOI:10.1186/s42522-024-00104-w   PDF(Pubmed)

Abstract:
Oropouche and Mayaro viruses are enzootic arboviruses of public health concern throughout Latin America. Recent outbreaks of OROV in northern region and sporadic autochthonous cases in western region of Brazil, suggest a silent circulation of these neglected viruses. Aiming to investigate the exposure of different species of domestic animals to MAYV and OROV in urban and peri-urban areas of West-Central Brazil, we performed a cross-sectional serosurvey by plaque reduction neutralization test (PRNT). Our findings included neutralizing antibodies for both arboviruses in cattle, dogs and horses, suggesting eventual role of domestic animals in enzootic arbovirus surveillance in Brazil.
摘要:
Oropouche和Mayaro病毒是整个拉丁美洲引起公共卫生关注的地方性虫媒病毒。最近在北部地区爆发了OROV,在巴西西部地区零星爆发了本地病例,表明这些被忽视的病毒的沉默循环。旨在调查巴西中西部城市和城市周边地区不同种类的家畜对MAYV和OROV的暴露情况,我们通过斑块减少中和试验(PRNT)进行了横断面血清调查.我们的发现包括牛体内两种虫媒病毒的中和抗体,狗和马,提示家畜在巴西的地方性虫媒病毒监测中的最终作用。
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