Abstract：
Cryptosporidium species, causing diarrheal illnesses in humans and animals worldwide, are under investigation for their molecular epidemiology in Japan. The study focuses on detecting Cryptosporidium species in humans, animals, water, and the environment, revealing three species in people: C. parvum, C. meleagridis, and C. hominis. Subtype IIa of the C. parvum gp60 gene is prevalent, indicating potential zoonotic transmission. Animal studies identified sixteen species, mainly cattle and pets, with C. parvum (subtype IIa) common in cattle and C. canis and C. felis prevalent in pets. Additionally, C. bovis and C. ryanae were found in cattle and sika deer. Knowledge gaps exist, particularly in water and environmental source typing, with limited research revealing five species and five genotypes, suggesting a significant role of water in transmission. Further research is needed to understand the molecular diversity and transmission dynamics across humans, animals, water, and the environment in Japan.
摘要：
隐孢子虫物种，在全世界的人类和动物中引起腹泻疾病，正在日本接受分子流行病学调查。这项研究的重点是检测人类中的隐孢子虫物种，动物,水,和环境，揭示了人类的三个物种：C.parvum，C.meleagridis,还有C.hominis.C.parvumgp60基因的IIa亚型很普遍，表明潜在的人畜共患传播。动物研究确定了16个物种，主要是牛和宠物，C.parvum（亚型IIa）常见于牛，C.canis和C.felis在宠物中普遍存在。此外,在牛和梅花鹿中发现了C.bovis和C.ryanae。存在知识差距,特别是在水和环境来源类型中，有限的研究揭示了五种物种和五种基因型，表明水在传播中的重要作用。需要进一步的研究来了解整个人类的分子多样性和传播动力学，动物,水,以及日本的环境。
