关键词: Nodular regenerative hyperplasia Non-cirrhotic portal hypertension Porto-sinusoidal vascular disease

Mesh : Humans Hypertension, Portal / etiology diagnosis complications epidemiology Hepatic Veno-Occlusive Disease / etiology diagnosis Portal Vein / pathology

来  源:   DOI:10.1016/j.cld.2024.03.004

Abstract:
Porto-sinusoidal vascular disease (PSVD) is the medical diagnosis for a patient who has portal hypertension in the absence of cirrhosis on liver biopsy. There are several specific histologic findings for PSVD, including obliterative portal venopathy, nodular regenerative hyperplasia, and incomplete septal fibrosis. Epidemiologic reports vary widely among regions; PSVD comprises less than 10% of causes of portal hypertension in Western countries but incidence has been found to be as high as 48% in India. There is an expansive list of etiologies that have been reported to cause PSVD.
摘要:
窦口血管疾病(PSVD)是肝活检中没有肝硬化的门静脉高压症患者的医学诊断。PSVD有几种特定的组织学发现,包括闭塞性门静脉病,结节性再生增生,和不完全的间隔纤维化。各地区的流行病学报告差异很大;在西方国家,PSVD占门静脉高压症病因的不到10%,但在印度,发病率高达48%。据报道,有大量的病因导致PSVD。
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