关键词: Edible uses Ethnopharmacology Lablab Semen Album Pharmacology Phytochemistry

来  源:   DOI:10.1016/j.jep.2024.118507

Abstract:
BACKGROUND: Lablab Semen Album (lablab), the white and dried mature fruit of Lablab purpureus in the Lablab genus of the Fabaceae family, is a renowned traditional medicinal herb with a long history of use in China. In Chinese medicine, lablab is often combined with other drugs to treat conditions such as weak spleen and stomach, loss of appetite, loose stools, excessive leucorrhoea, summer dampness and diarrhea, chest tightness, and abdominal distension.
METHODS: Comprehensive information on lablab was gathered from databases including Web of Science, Science Direct, Google Scholar, Springer, PubMed, CNKI, Wanfang, and ancient materia medica.
RESULTS: Lablab, a member of the lentil family, thrives in warm and humid climates, and is distributed across tropical and subtropical regions worldwide. Traditionally, lablab is used to treat various ailments, such as spleen and stomach weakness, loss of appetite, and diarrhea. Phytochemical analyses reveal that lablab is a rich source of triterpenoid saponins, glucosides, volatile oils, polysaccharides, and amino acids. Lablab extracts exhibit diverse biological activities, including hypolipidemic, hypoglycemic, immunomodulatory, antioxidant, hepatoprotective, antitumoral, antiviral properties, and more. Besides its medicinal applications, lablab is extensively used in the food industry due to its high nutrient content. Additionally, the quality of lablab can be regulated by determining the levels of key chemical components pivotal to its medicinal effects, ensuring the herb\'s overall quality.
CONCLUSIONS: Lablab is a promising medicinal and edible plant ingredient with diverse pharmacological effects, making it a valuable ingredient for food, pharmaceuticals, and animal husbandry. However, it has inherent toxicity if not properly prepared. Additionally, some traditional uses and pharmacological activities lack scientific validation due to incomplete methods, unclear results, and insufficient clinical data. Thus, further in vivo and in vitro studies on its pharmacology, pharmacokinetics, and toxicology, along with clinical efficacy evaluations, are needed to ensure lablab\'s safety and effectiveness. As an important traditional Chinese medicine, lablab deserves more attention.
摘要:
背景:Lablab精液专辑(Lablab),在豆科的Lablab属中,Lablabpurpureus的白色和干燥的成熟果实,是一种著名的传统药草,在中国有着悠久的使用历史。在中医方面,lablab通常与其他药物联合治疗脾胃虚弱等疾病,食欲不振,松散的粪便,白带过多,夏季潮湿和腹泻,胸闷,和腹胀.
方法:实验室的综合信息来自WebofScience等数据库,科学直接,谷歌学者,Springer,PubMed,CNKI,万方,和古老的本草。
结果:Lablab,扁豆家族的一员,在温暖潮湿的气候中茁壮成长,分布在世界各地的热带和亚热带地区。传统上,实验室用于治疗各种疾病,比如脾胃虚弱,食欲不振,和腹泻。植物化学分析表明,lablab是三萜皂苷的丰富来源,葡糖苷,挥发油,多糖,和氨基酸。Lablab提取物表现出多种生物活性,包括降血脂,低血糖,免疫调节,抗氧化剂,保肝,抗肿瘤,抗病毒特性,还有更多.除了它的医疗应用,lablab由于其高营养成分而被广泛用于食品工业。此外,lablab的质量可以通过确定其药用效果关键的关键化学成分的水平来调节,确保草药的整体质量。
结论:Lablab是一种有前途的药用和食用植物成分,具有多种药理作用,使其成为有价值的食物成分,制药,和畜牧业。然而,如果不适当制备,它具有固有毒性。此外,由于方法不完整,一些传统用途和药理活性缺乏科学验证,结果不明确,和不足的临床数据。因此,对其药理学进行进一步的体内和体外研究,药代动力学,和毒理学,随着临床疗效评估,需要确保实验室的安全性和有效性。作为一种重要的中药,Lablab值得更多关注。
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