Abstract：
To reduce environmental pollution and improve human health, developing green active food packaging materials is very necessary. In this study, a novel antioxidant and antibacterial composite film was produced by incorporating inclusion complex (CDIC) of cannabidiol (CBD) with 2,6-di-O-methyl-β-cyclodextrin (DM-β-CD) into pectin. The pectin films loaded with CBD and hemp leaf water extract (HLE) were prepared for comparison. Comprehensive characterizations showed CBD was encapsulated by DM-β-CD and CDIC was evenly dispersed into pectin matrix, forming the compact and intact film. The composite films showed good mechanical properties and biodegradability. CDIC film showed the highest transparency and smoothness (Rrms/Rmax: 2.6/16.8 nm). The addition of bioactives reduced the water-binding capacity and CDIC film had the strongest hydrophobicity. Besides, DM-β-CD encapsulation improved the thermal stability of CBD in CDIC film. Benefiting from encapsulation and excellent bioactivities of CBD, CDIC film showed excellent antioxidant capacity and antibacterial activity, effectively inhibiting colony growth and maintaining the strawberry color in strawberry preservation. This work could provide a novel eco-friendly candidate for food packaging material and expand the use of CBD in food industry.
摘要：
减少环境污染，提高人体健康水平，开发绿色活性食品包装材料是非常必要的。在这项研究中,通过将大麻二酚（CBD）与2,6-二-O-甲基-β-环糊精（DM-β-CD）的包合物（CDIC）掺入果胶中，制备了一种新型的抗氧化和抗菌复合膜。制备负载有CBD和大麻叶水提取物(HLE)的果胶膜用于比较。综合表征显示CBD被DM-β-CD包裹，CDIC均匀分散在果胶基质中，形成紧凑和完整的薄膜。复合薄膜表现出良好的力学性能和生物降解性。CDIC膜显示出最高的透明度和平滑度(Rrms/Rmax:2.6/16.8nm)。生物活性剂的添加降低了水结合能力，并且CDIC膜具有最强的疏水性。此外,DM-β-CD封装提高了CDIC膜中CBD的热稳定性。受益于CBD的封装和出色的生物活性，CDIC膜表现出优异的抗氧化能力和抗菌活性,在草莓保鲜中有效抑制菌落生长,保持草莓色泽。这项工作可以为食品包装材料提供一种新型的生态友好型候选材料，并扩大CBD在食品工业中的用途。
