关键词: Obesity treatment Patient perspective Personalised medicine Qualitative

来  源:   DOI:10.1016/j.orcp.2024.06.004

Abstract:
OBJECTIVE: Personalised medicine is seen as an exciting opportunity to improve the health outcomes of people with obesity. As research on phenotyping and personalised treatment for obesity rapidly advances, this study sought to understand patient preferences and perspectives on personalised medicine for obesity.
METHODS: A participatory world café methodology was used to garner the perspectives of people living with obesity on the potential opportunities and limitations associated with a personalised approach to obesity risk identification and treatment. Data were recorded by participants on tablemats and analysed thematically using thematic analysis.
RESULTS: Patients expressed the hope that personalised medicine for obesity would reduce stigma, support understanding of obesity as a disease, and improve treatment outcomes and acceptance. They also expressed concern about the accuracy of personalised medicine for obesity, its implications for insurance and that further advances in individual, personalised medicine, would detract attention from social, environmental, economic and psychological drivers of obesity.
CONCLUSIONS: This study highlights how patients are generally very optimistic about the potential for personalised obesity medicine but also raise a number of legitimate concerns that will be of interest to clinicians, industry, and policy makers.
摘要:
目的:个性化医疗被视为改善肥胖者健康状况的一个令人兴奋的机会。随着肥胖的表型和个性化治疗的研究迅速发展,这项研究旨在了解患者对肥胖个性化医疗的偏好和观点。
方法:使用参与式世界咖啡馆方法来了解肥胖患者对与肥胖风险识别和治疗的个性化方法相关的潜在机会和局限性的看法。参与者在桌子上记录数据,并使用主题分析进行主题分析。
结果:患者表示希望针对肥胖的个性化医疗可以减少耻辱,支持理解肥胖是一种疾病,并提高治疗结果和接受度。他们还对肥胖个性化医疗的准确性表示担忧,它对保险的影响以及个人的进一步发展,个性化医疗,会分散社会的注意力,环境,肥胖的经济和心理驱动因素。
结论:这项研究强调了患者普遍对个性化肥胖药物的潜力非常乐观,但也提出了一些临床医生感兴趣的合理问题。工业,和政策制定者。
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