关键词: Familial hyperparathyroidism Persistent hyperparathyroidism Primary hyperparathyroidism Recurrent hyperparathyroidism Reoperative parathyroidectomy

Mesh : Humans Hyperparathyroidism, Primary / surgery diagnosis genetics Parathyroidectomy / methods Recurrence Reoperation Parathyroid Neoplasms / surgery genetics diagnosis complications

来  源:   DOI:10.1016/j.suc.2024.02.010

Abstract:
Primary hyperparathyroidism can be sporadic or part of a genetic syndrome, such as MEN1 or HPT-JT. Diagnosis of hereditary HPT requires a thorough history and physical. Parathyroidectomy is curative with greater than 95% success. However, some patients have persistent or recurrent disease requiring reoperation. Reoperative parathyroidectomy is technically challenging, and localizing the pathologic gland can difficult. Patients needing reoperation should undergo evaluation by a high-volume surgeon. Care should be taken to obtain all of the preoperative workup and operative note from the initial surgery. Radioguided parathyroidectomy can be safely and effectively performed in patients with hereditary HPT or undergoing reoperative surgery.
摘要:
原发性甲状旁腺功能亢进可以是散发性或遗传综合征的一部分,如MEN1或HPT-JT。遗传性HPT的诊断需要全面的病史和体格检查。甲状旁腺切除术可治愈,成功率超过95%。然而,一些患者患有持续性或复发性疾病,需要再次手术。再次手术甲状旁腺切除术在技术上具有挑战性,定位病理腺体可能很困难。需要再次手术的患者应接受大量外科医生的评估。应注意从最初的手术中获得所有的术前检查和手术记录。对于遗传性HPT或接受再次手术的患者,可以安全有效地进行放射性甲状旁腺切除术。
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