Abstract：
UNASSIGNED: Congenital gangrene of the limb in a newborn child is an extremely rare pathology with polyetiological causes that has not been fully studied. Therefore, each case of this pathology has its own characteristics of manifestations and allows you to get closer to solving this problem.
METHODS: We present a clinical case of congenital gangrene of the right upper limb in a newborn child. Analysis of the newborn baby\'s medical history indicated gestational hypertension and pyelonephritis during pregnancy in the mother, hemostasis disorders in the newborn. Computed tomography (CT) of the vessels of the right upper limb and thoracic segment confirmed brachial artery thrombosis. At the initial stage, conservative treatment was carried out, which included preventive antibacterial therapy and local care of the affected area. Only after a clear delineation of the dead tissue, the amputation of the segment of the right upper limb was performed. Amputation was performed with preservation of the proximal growth zone in order to provide an adequate stump for subsequent prosthetics.
UNASSIGNED: Adverse factors during pregnancy can cause increased thrombosis. Through fetal communications, blood clots from the right atrium can enter the left atrium, the left ventricle and further into the large circulatory circle and cause thrombosis of the artery of the right upper limb. Another factor of increased thrombosis is congenital intrauterine infection of the newborn. Conservative treatment is carried out after diagnosis until the final determination of the boundaries of gangrene. When performing amputation, it is important to preserve the proximal bone growth zone in order to form an adequate stump for prosthetics.
CONCLUSIONS: Congenital gangrene of the limb in a newborn child is an extremely rare pathology. Irreversible changes in the upper limb in the child were caused by a combination of two factors: gestational hypertension and pyelonephritis in a pregnant woman and hemostasis disorders in a newborn due to intrauterine infection. Therefore, the preparation of women for pregnancy, examination for intrauterine infection and treatment of extragenital pathology are important in the prevention of this disease.
METHODS: We present a clinical case of congenital gangrene of the right upper limb in a newborn child. Analysis of the newborn baby\'s medical history indicated gestational hypertension and pyelonephritis during pregnancy in the mother, hemostasis disorders in the newborn. Computed tomography (CT) of the vessels of the right upper limb and thoracic segment confirmed brachial artery thrombosis. At the initial stage, conservative treatment was carried out, which included preventive antibacterial therapy and local care of the affected area. Only after a clear delineation of the dead tissue, the amputation of the segment of the right upper limb was performed. Amputation was performed with preservation of the proximal growth zone in order to provide an adequate stump for subsequent prosthetics.
UNASSIGNED: Adverse factors during pregnancy can cause increased thrombosis. Through fetal communications, blood clots from the right atrium can enter the left atrium, the left ventricle and further into the large circulatory circle and cause thrombosis of the artery of the right upper limb. Another factor of increased thrombosis is congenital intrauterine infection of the newborn. Conservative treatment is carried out after diagnosis until the final determination of the boundaries of gangrene. When performing amputation, it is important to preserve the proximal bone growth zone in order to form an adequate stump for prosthetics.
CONCLUSIONS: Congenital gangrene of the limb in a newborn child is an extremely rare pathology. Irreversible changes in the upper limb in the child were caused by a combination of two factors: gestational hypertension and pyelonephritis in a pregnant woman and hemostasis disorders in a newborn due to intrauterine infection. Therefore, the preparation of women for pregnancy, examination for intrauterine infection and treatment of extragenital pathology are important in the prevention of this disease.
摘要：
■新生儿的先天性肢体坏疽是一种极为罕见的病理，具有多病因原因，尚未得到充分研究。因此,这种病理的每种情况都有自己的表现特征，可以让你更接近解决这个问题。
方法：我们介绍一例新生儿右上肢先天性坏疽的临床病例。新生儿病史分析提示母亲妊娠期高血压和肾盂肾炎,新生儿的止血障碍。右上肢和胸段血管的计算机断层扫描（CT）证实了肱动脉血栓形成。在初始阶段,进行了保守治疗，其中包括预防性抗菌治疗和受影响地区的当地护理。只有在清晰地描绘了死亡组织之后，对右上肢段进行截肢。在保留近端生长区的情况下进行截肢，以便为随后的假肢提供足够的残端。
■怀孕期间的不良因素可导致血栓形成增加。通过胎儿通信，右心房的血凝块可以进入左心房,左心室并进一步进入大循环环，引起右上肢动脉血栓形成。血栓形成增加的另一个因素是新生儿的先天性宫内感染。在诊断后进行保守治疗，直到最终确定坏疽的边界。进行截肢时，重要的是要保留近端骨生长区，以便为假肢形成足够的残端。
结论：新生儿先天性肢体坏疽是一种极为罕见的病理。儿童上肢的不可逆变化是由两个因素共同引起的：孕妇的妊娠高血压和肾盂肾炎以及由于宫内感染引起的新生儿止血障碍。因此,妇女怀孕的准备，宫内感染的检查和生殖器外病理的治疗对预防这种疾病很重要。
方法：我们介绍一例新生儿右上肢先天性坏疽的临床病例。新生儿病史分析提示母亲妊娠期高血压和肾盂肾炎,新生儿的止血障碍。右上肢和胸段血管的计算机断层扫描（CT）证实了肱动脉血栓形成。在初始阶段,进行了保守治疗，其中包括预防性抗菌治疗和受影响地区的当地护理。只有在清晰地描绘了死亡组织之后，对右上肢段进行截肢。在保留近端生长区的情况下进行截肢，以便为随后的假肢提供足够的残端。
■怀孕期间的不良因素可导致血栓形成增加。通过胎儿通信，右心房的血凝块可以进入左心房,左心室并进一步进入大循环环，引起右上肢动脉血栓形成。血栓形成增加的另一个因素是新生儿的先天性宫内感染。在诊断后进行保守治疗，直到最终确定坏疽的边界。进行截肢时，重要的是要保留近端骨生长区，以便为假肢形成足够的残端。
结论：新生儿先天性肢体坏疽是一种极为罕见的病理。儿童上肢的不可逆变化是由两个因素共同引起的：孕妇的妊娠高血压和肾盂肾炎以及由于宫内感染引起的新生儿止血障碍。因此,妇女怀孕的准备，宫内感染的检查和生殖器外病理的治疗对预防这种疾病很重要。
