Abstract：
OBJECTIVE: What is the attitude of Belgian women of reproductive age towards enucleated egg donation? Does the willingness of women to donate differ when they would donate enucleated or whole eggs?
METHODS: In 2022, an online survey was conducted among a representative sample of 1000 women in Belgium aged 18-50 years. The item on willingness to anonymously donate enucleated eggs was dichotomized into those willing to donate and those not willing to donate or uncertain.
RESULTS: No statistically significant difference was found between the willingness to donate enucleated eggs and whole eggs (whether anonymously or identifiably). Anonymity, however, affected the willingness to donate, with considerably fewer women willing to donate identifiably. The respondents were divided about their parental status if they were to donate enucleated eggs, with less than one-half (44%) not considering themselves to be a genetic mother. Women willing to donate enucleated eggs anonymously were less likely to view themselves as a genetic mother of the child compared with others. Fewer than one in five considered the technique unacceptable because the resulting child would carry genetic material of three persons.
CONCLUSIONS: Women in the general population did not show a greater willingness to donate enucleated eggs than whole eggs. The fact that the respondents were strongly divided on whether or not they would consider themselves to be a genetic mother of the resulting child may explain this result. Other factors, such as the potential high risk for the child, may also have contributed to less willingness.
METHODS: In 2022, an online survey was conducted among a representative sample of 1000 women in Belgium aged 18-50 years. The item on willingness to anonymously donate enucleated eggs was dichotomized into those willing to donate and those not willing to donate or uncertain.
RESULTS: No statistically significant difference was found between the willingness to donate enucleated eggs and whole eggs (whether anonymously or identifiably). Anonymity, however, affected the willingness to donate, with considerably fewer women willing to donate identifiably. The respondents were divided about their parental status if they were to donate enucleated eggs, with less than one-half (44%) not considering themselves to be a genetic mother. Women willing to donate enucleated eggs anonymously were less likely to view themselves as a genetic mother of the child compared with others. Fewer than one in five considered the technique unacceptable because the resulting child would carry genetic material of three persons.
CONCLUSIONS: Women in the general population did not show a greater willingness to donate enucleated eggs than whole eggs. The fact that the respondents were strongly divided on whether or not they would consider themselves to be a genetic mother of the resulting child may explain this result. Other factors, such as the potential high risk for the child, may also have contributed to less willingness.
摘要：
目标：比利时育龄妇女对去核卵子捐赠的态度如何？妇女捐赠去核卵子或全卵的意愿是否不同？
方法：2022年，对比利时1000名18-50岁妇女的代表性样本进行了在线调查。关于匿名捐赠去核卵子的意愿被分为愿意捐赠和不愿意捐赠或不确定的人。
结果：捐赠去核卵和全卵（无论是匿名还是可识别）的意愿之间没有统计学上的显着差异。匿名,然而,影响了捐赠的意愿，愿意捐赠的女性要少得多。如果他们捐赠去核卵子，受访者对他们的父母身份存在分歧，不到一半(44%)的人不认为自己是遗传母亲。与其他人相比，愿意匿名捐赠去核卵子的女性不太可能将自己视为孩子的遗传母亲。不到五分之一的人认为该技术不可接受，因为由此产生的孩子将携带三人的遗传物质。
结论：普通人群中的女性并没有表现出比全卵更愿意捐赠去核卵。受访者在是否认为自己是孩子的遗传母亲方面存在强烈分歧，这一事实可以解释这一结果。其他因素,比如孩子的潜在高风险，也可能导致意愿降低。
方法：2022年，对比利时1000名18-50岁妇女的代表性样本进行了在线调查。关于匿名捐赠去核卵子的意愿被分为愿意捐赠和不愿意捐赠或不确定的人。
结果：捐赠去核卵和全卵（无论是匿名还是可识别）的意愿之间没有统计学上的显着差异。匿名,然而,影响了捐赠的意愿，愿意捐赠的女性要少得多。如果他们捐赠去核卵子，受访者对他们的父母身份存在分歧，不到一半(44%)的人不认为自己是遗传母亲。与其他人相比，愿意匿名捐赠去核卵子的女性不太可能将自己视为孩子的遗传母亲。不到五分之一的人认为该技术不可接受，因为由此产生的孩子将携带三人的遗传物质。
结论：普通人群中的女性并没有表现出比全卵更愿意捐赠去核卵。受访者在是否认为自己是孩子的遗传母亲方面存在强烈分歧，这一事实可以解释这一结果。其他因素,比如孩子的潜在高风险，也可能导致意愿降低。
