Abstract：
BACKGROUND: The Knowledge Translation (KT) Programme of a pan-Canadian strategic patient-oriented research network focused on brain-based developmental disabilities aimed to mobilize knowledge relevant to the network members. The programme also promotes and studies integrated Knowledge Translation (iKT) approaches involving different interested parties, such as researchers, patient-partners and decision-makers, in all parts of the knowledge creation process.
OBJECTIVE: The objective of this study is to advance research programme evaluation methods through a realist evaluation of the process of implementing iKT activities.
METHODS: Realist process evaluation included: (1) development of initial programme theories (using the partnership synergy theory); (2) data collection and analysis; (3) synthesis and refinement of theories through engagement with literature; and (4) presentation of findings in context-mechanism-outcome (C-M-O) configurations. A range of project documentation records were reviewed for analysis, and three co-leads, a programme coordinator, and a senior research associate were consulted to contextualize the implementation process of relevant KT activities.
RESULTS: Based on the developed C-M-O configurations, we identified five key mechanisms of generating synergy in the iKT processes: (1) Visible shared leadership that embodies what iKT looks like; (2) Researchers\' readiness for iKT; (3) Adaptation and flexible allocation of resources to emerging needs; (4) Power sharing to create practical and creative knowledge; and (5) Collective voice for potential transformative impacts at the policy level.
CONCLUSIONS: The current realist evaluation demonstrated how partnerships between researchers, patient-partners and other interested parties can synergistically generate new ways of thinking among all interested parties, actionable strategies to integrate users in research, and solutions to disseminate knowledge. In particular, we identified a pivotal role for patient-partners to act as equal decision-maker helps building and maintaining partnerships and consolidating KT strategies.
OBJECTIVE: The objective of this study is to advance research programme evaluation methods through a realist evaluation of the process of implementing iKT activities.
METHODS: Realist process evaluation included: (1) development of initial programme theories (using the partnership synergy theory); (2) data collection and analysis; (3) synthesis and refinement of theories through engagement with literature; and (4) presentation of findings in context-mechanism-outcome (C-M-O) configurations. A range of project documentation records were reviewed for analysis, and three co-leads, a programme coordinator, and a senior research associate were consulted to contextualize the implementation process of relevant KT activities.
RESULTS: Based on the developed C-M-O configurations, we identified five key mechanisms of generating synergy in the iKT processes: (1) Visible shared leadership that embodies what iKT looks like; (2) Researchers\' readiness for iKT; (3) Adaptation and flexible allocation of resources to emerging needs; (4) Power sharing to create practical and creative knowledge; and (5) Collective voice for potential transformative impacts at the policy level.
CONCLUSIONS: The current realist evaluation demonstrated how partnerships between researchers, patient-partners and other interested parties can synergistically generate new ways of thinking among all interested parties, actionable strategies to integrate users in research, and solutions to disseminate knowledge. In particular, we identified a pivotal role for patient-partners to act as equal decision-maker helps building and maintaining partnerships and consolidating KT strategies.
摘要：
背景：泛加拿大面向患者的战略研究网络的知识翻译（KT）计划专注于基于大脑的发育障碍，旨在动员与网络成员相关的知识。该计划还促进和研究涉及不同利益方的综合知识翻译（iKT）方法，比如研究人员，患者伙伴和决策者，在知识创造过程的各个部分。
目的：本研究的目的是通过对实施iKT活动的过程进行现实评估来推进研究计划评估方法。
方法：现实主义过程评估包括：（1）初始计划理论的发展（使用伙伴关系协同理论）；（2）数据收集和分析；（3）通过与文献接触来综合和完善理论；（4）在上下文机制结果（C-M-O）配置中呈现结果。审查了一系列项目文件记录进行分析，和三个共同领导，方案协调员，并咨询了一名高级研究助理，以了解相关KT活动的实施过程。
结果：基于开发的C-M-O配置，我们确定了在iKT过程中产生协同作用的五个关键机制：（1）体现iKT外观的可见共享领导；（2）研究人员为iKT做好准备；（3）适应和灵活分配资源以适应新出现的需求；（4）权力共享以创造实用和创造性的知识；（5）在政策层面对潜在的变革性影响的集体声音。
结论：当前的现实主义评估证明了研究人员之间的伙伴关系，患者-合作伙伴和其他相关方可以在所有相关方之间协同产生新的思维方式，在研究中整合用户的可操作策略，以及传播知识的解决方案。特别是,我们确定了患者-合作伙伴作为平等的决策者在帮助建立和维持伙伴关系以及巩固KT战略方面的关键作用.
目的：本研究的目的是通过对实施iKT活动的过程进行现实评估来推进研究计划评估方法。
方法：现实主义过程评估包括：（1）初始计划理论的发展（使用伙伴关系协同理论）；（2）数据收集和分析；（3）通过与文献接触来综合和完善理论；（4）在上下文机制结果（C-M-O）配置中呈现结果。审查了一系列项目文件记录进行分析，和三个共同领导，方案协调员，并咨询了一名高级研究助理，以了解相关KT活动的实施过程。
结果：基于开发的C-M-O配置，我们确定了在iKT过程中产生协同作用的五个关键机制：（1）体现iKT外观的可见共享领导；（2）研究人员为iKT做好准备；（3）适应和灵活分配资源以适应新出现的需求；（4）权力共享以创造实用和创造性的知识；（5）在政策层面对潜在的变革性影响的集体声音。
结论：当前的现实主义评估证明了研究人员之间的伙伴关系，患者-合作伙伴和其他相关方可以在所有相关方之间协同产生新的思维方式，在研究中整合用户的可操作策略，以及传播知识的解决方案。特别是,我们确定了患者-合作伙伴作为平等的决策者在帮助建立和维持伙伴关系以及巩固KT战略方面的关键作用.
