关键词: Alcoholic Liver disease IgA nephropathy IgA vasculitis rapidly progressive glomerulonephritis

Mesh : Humans Male Glomerulonephritis, IGA / complications diagnosis Middle Aged Disease Progression Liver Diseases, Alcoholic / complications IgA Vasculitis / complications diagnosis drug therapy Vasculitis / complications etiology diagnosis drug therapy

来  源:   DOI:10.69097/41-03-2024-09

Abstract:
IgA nephropathy (IgAN) is a fairly common association with alcoholic liver disease. However, IgA vasculitis (IgAV) is quite an uncommon association with alcoholic liver cirrhosis and only a handful of cases have been reported in literature. Secondary IgAN usually presents in a docile manner, progressing slowly in about 5-25 years. It is usually responsive to steroid therapy, very rarely progressing to End-Stage Renal Disease. Here, we present a man in his late 50s, a known hypertensive and alcohol related liver-cirrhotic, who presented to our hospital with rash and rapidly progressive renal failure (RPRF). He was diagnosed with IgA nephritis with IgA vasculitis (IgAVN). His diagnosis was confirmed with skin and renal biopsy. He was started on renal replacement therapy for his renal failure and began oral steroid therapy. After administration of steroid therapy for 6 months, the patient recovered and was dialysis independent with stable renal parameters.
摘要:
IgA肾病(IgAN)与酒精性肝病相当常见。然而,IgA血管炎(IgAV)与酒精性肝硬化的关系并不常见,文献中仅报道了少数病例。继发性IgAN通常以温顺的方式出现,在大约5-25年内进展缓慢。它通常对类固醇治疗有反应,很少进展为终末期肾病。这里,我们介绍一个50多岁的男人,一种已知的高血压和酒精相关的肝硬化,他因皮疹和快速进行性肾功能衰竭(RPRF)就诊于我们医院。他被诊断为IgA肾炎伴IgA血管炎(IgAVN)。皮肤和肾活检证实了他的诊断。他因肾功能衰竭开始接受肾脏替代治疗,并开始口服类固醇治疗。给予类固醇治疗6个月后,患者康复,且独立于透析,肾脏参数稳定.
公众号