PDF(Pubmed)
Abstract：
BACKGROUND: Many people struggle with the choice in a series of processes, from prostate cancer (PCa) diagnosis to treatment. We investigated the degree of regret after the prostate biopsy (PBx) and relevant factors in patients recommended for biopsy for suspected PCa.
METHODS: From 06/2020 to 05/2022, 198 people who performed PBx at three institutions were enrolled and analyzed through a questionnaire before and after biopsy. Before the biopsy, a questionnaire was conducted to evaluate the sociodemographic information, anxiety scale, and health literacy, and after PBx, another questionnaire was conducted to evaluate the decision regret scale. For patients diagnosed as PCa after biopsy, a questionnaire was conducted when additional tests were performed at PCa staging work-up.
RESULTS: 190 patients answered the questionnaire before and after PBx. The mean age was 66.2 ± 7.8 years. Overall, 5.5% of men regretted biopsy, but there was no significant difference between groups according to the PCa presence. Multivariate analysis, to identify predictors for regret, revealed that the case when physicians did not properly explain what the prostate-specific antigen (PSA) test was like and what PSA elevation means (OR 20.57, [95% CI 2.45-172.70], p = 0.005), low media literacy (OR 10.01, [95% CI 1.09-92.29], p = 0.042), and when nobody to rely on (OR 8.49, [95% CI 1.66-43.34], p = 0.010) were significantly related.
CONCLUSIONS: Overall regret related to PBx was low. Decision regret was more significantly related to media literacy rather than to educational level. For patients with relatively low media literacy and fewer people to rely on in case of serious diseases, more careful attention and counseling on PBx, including a well-informed explanation on PSA test, is helpful.
METHODS: From 06/2020 to 05/2022, 198 people who performed PBx at three institutions were enrolled and analyzed through a questionnaire before and after biopsy. Before the biopsy, a questionnaire was conducted to evaluate the sociodemographic information, anxiety scale, and health literacy, and after PBx, another questionnaire was conducted to evaluate the decision regret scale. For patients diagnosed as PCa after biopsy, a questionnaire was conducted when additional tests were performed at PCa staging work-up.
RESULTS: 190 patients answered the questionnaire before and after PBx. The mean age was 66.2 ± 7.8 years. Overall, 5.5% of men regretted biopsy, but there was no significant difference between groups according to the PCa presence. Multivariate analysis, to identify predictors for regret, revealed that the case when physicians did not properly explain what the prostate-specific antigen (PSA) test was like and what PSA elevation means (OR 20.57, [95% CI 2.45-172.70], p = 0.005), low media literacy (OR 10.01, [95% CI 1.09-92.29], p = 0.042), and when nobody to rely on (OR 8.49, [95% CI 1.66-43.34], p = 0.010) were significantly related.
CONCLUSIONS: Overall regret related to PBx was low. Decision regret was more significantly related to media literacy rather than to educational level. For patients with relatively low media literacy and fewer people to rely on in case of serious diseases, more careful attention and counseling on PBx, including a well-informed explanation on PSA test, is helpful.
摘要：
背景：许多人在一系列过程中为选择而苦苦挣扎，从前列腺癌（PCa）诊断到治疗。我们调查了前列腺活检（PBx）后的遗憾程度以及建议对可疑PCa进行活检的患者的相关因素。
方法：从2020年6月至2022年5月5日，在三个机构进行PBx的198人被招募并通过活检前后的问卷调查进行分析。活检前,进行了问卷调查以评估社会人口统计信息，焦虑量表，和健康素养，在PBx之后，另一份问卷用于评估决策后悔量表。对于活检后诊断为PCa的患者，在PCa分期检查时进行额外检查时,我们进行了问卷调查.
结果：190名患者在PBx前后回答了问卷。平均年龄为66.2±7.8岁。总的来说,5.5%的男性后悔活检，但是根据PCa的存在，组间没有显着差异。多变量分析，为了确定后悔的预测因素，揭示了医生没有正确解释前列腺特异性抗原（PSA）测试是什么样的以及PSA升高意味着什么的情况（OR20.57，[95％CI2.45-172.70]，p=0.005),低媒体素养(OR10.01，[95%CI1.09-92.29]，p=0.042),当没有人可以依赖时(OR8.49，[95%CI1.66-43.34]，p=0.010)呈显著相关。
结论：与PBx相关的总体遗憾程度较低。决策遗憾与媒体素养有关，而不是与教育水平有关。对于媒介素养相对较低，在发生严重疾病时依赖较少的患者，对PBx的更仔细的关注和咨询，包括对PSA测试的明智解释，是有帮助的。
方法：从2020年6月至2022年5月5日，在三个机构进行PBx的198人被招募并通过活检前后的问卷调查进行分析。活检前,进行了问卷调查以评估社会人口统计信息，焦虑量表，和健康素养，在PBx之后，另一份问卷用于评估决策后悔量表。对于活检后诊断为PCa的患者，在PCa分期检查时进行额外检查时,我们进行了问卷调查.
结果：190名患者在PBx前后回答了问卷。平均年龄为66.2±7.8岁。总的来说,5.5%的男性后悔活检，但是根据PCa的存在，组间没有显着差异。多变量分析，为了确定后悔的预测因素，揭示了医生没有正确解释前列腺特异性抗原（PSA）测试是什么样的以及PSA升高意味着什么的情况（OR20.57，[95％CI2.45-172.70]，p=0.005),低媒体素养(OR10.01，[95%CI1.09-92.29]，p=0.042),当没有人可以依赖时(OR8.49，[95%CI1.66-43.34]，p=0.010)呈显著相关。
结论：与PBx相关的总体遗憾程度较低。决策遗憾与媒体素养有关，而不是与教育水平有关。对于媒介素养相对较低，在发生严重疾病时依赖较少的患者，对PBx的更仔细的关注和咨询，包括对PSA测试的明智解释，是有帮助的。
