Abstract：
BACKGROUND: Projection and upper rotation to the tip is fundamental in the nasal rejuvenation, as a matter of fact the tip is the most important and has strongly effects on the improve appearance and quality of life. The aim of the present study was to evaluate reshaping the tip of the nose by cross-linked hyaluronic acid using Italian technique.
METHODS: In a period between November 2019 and 2023, a total of one hundred and forty healthy, 95 females and 45 man patients, were performed with a mean age 44±5 (age range: 31-52 years old) affected by tip of congenital (22) or ageing nose hypotonia (118), and reduced volume that need of an elevation of the nose tip. The anatomic markers have been considered for the anthropometric measurements after the filler rhinoplasty. Two infiltrations were performed, one in the infiltration into the antero-caudal access over the columella produce upward rotation of the tip of the nose and second infiltration into the antero-superior access produce the projection of the tip of the nose. Medical device used in the study was Neofound STRUCT LIDO (LOVE COSMEDICAL srls-Via Toniolo 9, 57022 Castagneto Carducci, ITALY) containing sodium hyaluronate/hyaluronic acid high molecular weight (1.500RESULTS: The effect on the upward rotation of the tip nose was evaluated using Global Aesthetic Improvement Scale and morphometric evaluation. All the subjects showed at least 2-3 grade improvement in GAIS score after HA filler injection. The analysis of patient satisfaction after the last follow-up visits clearly demonstrated good results. A significant morphometric difference was detected comparing the T0 and T90 (p<0,0001), while no difference was present comparing T90 and T180 means (p=0.11). The outcome of the present clinical study gives greater projection and upper rotation to the tip with great gratification of the patients and the surgeon. An augmentation of the tip nose with hyaluronic acid filler produces a rejuvenation of the nose area resulted in a more youthful appearance. No adverse event was observed. In 35 patients, additional HA infiltration had to be performed after 2 weeks.
CONCLUSIONS: In conclusion, the Italian technique descripted in the present paper is safe, simply, and efficacious for rejuvenation of the nose, with elevated levels of patient satisfaction.
METHODS: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
METHODS: In a period between November 2019 and 2023, a total of one hundred and forty healthy, 95 females and 45 man patients, were performed with a mean age 44±5 (age range: 31-52 years old) affected by tip of congenital (22) or ageing nose hypotonia (118), and reduced volume that need of an elevation of the nose tip. The anatomic markers have been considered for the anthropometric measurements after the filler rhinoplasty. Two infiltrations were performed, one in the infiltration into the antero-caudal access over the columella produce upward rotation of the tip of the nose and second infiltration into the antero-superior access produce the projection of the tip of the nose. Medical device used in the study was Neofound STRUCT LIDO (LOVE COSMEDICAL srls-Via Toniolo 9, 57022 Castagneto Carducci, ITALY) containing sodium hyaluronate/hyaluronic acid high molecular weight (1.500
CONCLUSIONS: In conclusion, the Italian technique descripted in the present paper is safe, simply, and efficacious for rejuvenation of the nose, with elevated levels of patient satisfaction.
METHODS: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
摘要：
背景：向尖端的投影和向上旋转是鼻部恢复活力的基础，事实上，提示是最重要的，对改善外观和生活质量有强烈的影响。本研究的目的是评估使用意大利技术通过交联透明质酸重塑鼻尖。
方法：在2019年11月至2023年期间，总共有一百四十人健康，95名女性和45名男性患者，进行了平均年龄44±5（年龄范围：31-52岁），受先天性鼻尖（22）或老化鼻张力减退（118）的影响，并减少需要鼻尖抬高的体积。填充隆鼻后的人体测量已考虑使用解剖标记。进行了两次渗透，一次渗入小柱上的前尾通道会导致鼻尖向上旋转，第二次渗入前上通道会导致鼻尖突出。研究中使用的医疗设备是NeofoundSTRUCTLIDO（LOVECOSMEDICALsrls-ViaToniolo9，57022CastagnetoCarducci，意大利）含透明质酸钠/透明质酸高分子量（1.500结果：使用整体美学改善量表和形态计量学评估评估了对鼻尖向上旋转的影响。所有受试者在HA填充剂注射后显示GAIS评分至少2-3级改善。最后一次随访后对患者满意度的分析清楚地表明了良好的效果。比较T0和T90(p<0.0001)，检测到显著的形态测量差异，而T90和T180平均值比较无差异(p=0.11)。本临床研究的结果为尖端提供了更大的投影和上旋转，使患者和外科医生非常满意。用透明质酸填充剂增加鼻尖，使鼻子区域恢复活力，从而使外观更加年轻。没有观察到不良事件。在35名患者中，2周后必须进行额外的HA浸润。
结论：结论：本文描述的意大利技术是安全的，简单地说,有效地恢复鼻子的活力，提高了患者的满意度。
方法：本期刊要求作者为每篇文章分配一定程度的证据。对于这些循证医学评级的完整描述，请参阅目录或在线作者说明www。springer.com/00266.
方法：在2019年11月至2023年期间，总共有一百四十人健康，95名女性和45名男性患者，进行了平均年龄44±5（年龄范围：31-52岁），受先天性鼻尖（22）或老化鼻张力减退（118）的影响，并减少需要鼻尖抬高的体积。填充隆鼻后的人体测量已考虑使用解剖标记。进行了两次渗透，一次渗入小柱上的前尾通道会导致鼻尖向上旋转，第二次渗入前上通道会导致鼻尖突出。研究中使用的医疗设备是NeofoundSTRUCTLIDO（LOVECOSMEDICALsrls-ViaToniolo9，57022CastagnetoCarducci，意大利）含透明质酸钠/透明质酸高分子量（1.500
结论：结论：本文描述的意大利技术是安全的，简单地说,有效地恢复鼻子的活力，提高了患者的满意度。
方法：本期刊要求作者为每篇文章分配一定程度的证据。对于这些循证医学评级的完整描述，请参阅目录或在线作者说明www。springer.com/00266.
