Abstract：
BACKGROUND: Ultrasonography (US) has become an essential tool for guiding botulinum neurotoxin (BoNT) injections in facial muscles, enhancing precision and safety. This narrative review explores the role of US in BoNT administration, particularly in complex anatomical regions, highlighting its impact on treatment customization, real-time visualization, and complication reduction.
METHODS: A comprehensive literature search was conducted using PubMed, MEDLINE, Embase, and Cochrane Library for articles published from January 2018 to December 2023. Search terms included \"Botulinum neurotoxin,\" \"facial anatomy,\" \"ultrasonography guided injection,\" and \"facial muscle sonoanatomy.\" Studies focusing on US-guided BoNT injections in facial muscles were included. Data extraction and synthesis were performed independently by two reviewers, focusing on study design, ultrasonography techniques, outcomes, and conclusions.
RESULTS: The review found that US guidance significantly enhances the precision of BoNT injections by providing real-time visualization of facial muscles and blood vessels, thereby reducing the risk of adverse events. US enables tailored injection strategies, ensuring symmetrical facial expressions and minimizing over-treatment. The technique also offers immediate feedback, allowing for on-the-spot adjustments to improve treatment efficacy and safety. However, the review identified limitations, including potential selection bias and variability in US techniques across different studies.
CONCLUSIONS: US guidance for BoNT injections into facial muscles offers substantial benefits in terms of precision, safety, and treatment customization. Despite the identified limitations, the integration of US into clinical practice is poised to enhance patient outcomes in aesthetic and therapeutic procedures. Further research is needed to standardize US techniques and broaden the inclusivity of studies to validate these findings comprehensively.
METHODS: A comprehensive literature search was conducted using PubMed, MEDLINE, Embase, and Cochrane Library for articles published from January 2018 to December 2023. Search terms included \"Botulinum neurotoxin,\" \"facial anatomy,\" \"ultrasonography guided injection,\" and \"facial muscle sonoanatomy.\" Studies focusing on US-guided BoNT injections in facial muscles were included. Data extraction and synthesis were performed independently by two reviewers, focusing on study design, ultrasonography techniques, outcomes, and conclusions.
RESULTS: The review found that US guidance significantly enhances the precision of BoNT injections by providing real-time visualization of facial muscles and blood vessels, thereby reducing the risk of adverse events. US enables tailored injection strategies, ensuring symmetrical facial expressions and minimizing over-treatment. The technique also offers immediate feedback, allowing for on-the-spot adjustments to improve treatment efficacy and safety. However, the review identified limitations, including potential selection bias and variability in US techniques across different studies.
CONCLUSIONS: US guidance for BoNT injections into facial muscles offers substantial benefits in terms of precision, safety, and treatment customization. Despite the identified limitations, the integration of US into clinical practice is poised to enhance patient outcomes in aesthetic and therapeutic procedures. Further research is needed to standardize US techniques and broaden the inclusivity of studies to validate these findings comprehensively.
摘要：
背景：超声检查（US）已成为指导肉毒杆菌神经毒素（BoNT）在面部肌肉中注射的重要工具，提高精度和安全性。这篇叙述性评论探讨了美国在BoNT管理中的作用，特别是在复杂的解剖区域，强调其对治疗定制的影响，实时可视化，减少并发症。
方法：使用PubMed进行了全面的文献检索，MEDLINE,Embase,和Cochrane图书馆，获取2018年1月至2023年12月发表的文章。搜索词包括“肉毒杆菌神经毒素，\“\”面部解剖学，\"\"超声引导注射,“和”面部肌肉超声解剖学。“研究重点是在面部肌肉中进行美国指导的BoNT注射。数据提取和合成由两名审阅者独立进行，专注于研究设计，超声检查技术,结果，和结论。
结果：评论发现，美国指南通过提供面部肌肉和血管的实时可视化，显着提高了BoNT注射的精度，从而降低不良事件的风险。美国启用量身定制的注射策略，确保对称的面部表情和尽量减少过度治疗。该技术还提供即时反馈，允许现场调整，以提高治疗疗效和安全性。然而,审查确定了局限性，包括不同研究中美国技术的潜在选择偏差和变异性。
结论：美国对面部肌肉注射BoNT的指导在精确度方面提供了巨大的好处，安全,和治疗定制。尽管有明显的局限性，将US纳入临床实践有望提高患者在美学和治疗过程中的预后.需要进一步的研究来标准化美国技术并扩大研究的包容性，以全面验证这些发现。
方法：使用PubMed进行了全面的文献检索，MEDLINE,Embase,和Cochrane图书馆，获取2018年1月至2023年12月发表的文章。搜索词包括“肉毒杆菌神经毒素，\“\”面部解剖学，\"\"超声引导注射,“和”面部肌肉超声解剖学。“研究重点是在面部肌肉中进行美国指导的BoNT注射。数据提取和合成由两名审阅者独立进行，专注于研究设计，超声检查技术,结果，和结论。
结果：评论发现，美国指南通过提供面部肌肉和血管的实时可视化，显着提高了BoNT注射的精度，从而降低不良事件的风险。美国启用量身定制的注射策略，确保对称的面部表情和尽量减少过度治疗。该技术还提供即时反馈，允许现场调整，以提高治疗疗效和安全性。然而,审查确定了局限性，包括不同研究中美国技术的潜在选择偏差和变异性。
结论：美国对面部肌肉注射BoNT的指导在精确度方面提供了巨大的好处，安全,和治疗定制。尽管有明显的局限性，将US纳入临床实践有望提高患者在美学和治疗过程中的预后.需要进一步的研究来标准化美国技术并扩大研究的包容性，以全面验证这些发现。
