关键词: deoxyhemoglobin magnetic susceptibility magnetization magneto-plethysmograph oxyhemoglobin

Mesh : Hemoglobins / analysis Humans Computer Simulation Plethysmography / methods Magnetic Fields Equipment Design Oxyhemoglobins / analysis

来  源:   DOI:10.1088/2057-1976/ad5cf7

Abstract:
The magneto-plethysmograph method is a combination of magnetic field and sensors used to detect changes in blood flow pulsation. However, to detect the magnetic properties of blood related to hemoglobin concentration, physical modeling and simulation are required. This approach involves designing simulations using magnetic field equations and magnetic susceptibility, where a permanent magnet is placed on the surface of blood vessels, and sensors based on giant magnetoresistance are placed at a distance r. The design originates from a simple approach involving the magnetization and detection of Fe atoms in hemoglobin. Parameters involved include the magnetic susceptibility of oxyhemoglobin and deoxyhemoglobin, with an external magnetic field exceeding 1 Tesla. From the physical modeling and simulation, graphs are obtained depicting the influence of hemoglobin concentration on the number of Fe atoms and its magnetization. This enables the design of non-invasive hemoglobin measurement sensor devices. The uniqueness of this simple physical model and simulation lies in its ability to produce specially designed device models for measuring hemoglobin concentration. This differs from other research focusing on blood flow pulse measurements; the results of this study provide new insights into the benefits of simple physics equations that can be developed for medical diagnostic research and device development.
摘要:
磁体积描记器方法是用于检测血流脉动变化的磁场和传感器的组合。然而,检测与血红蛋白浓度相关的血液的磁性,需要物理建模和仿真。这种方法涉及使用磁场方程和磁化率设计模拟,在血管表面放置永磁体,和基于巨磁阻的传感器放置在距离r处。该设计源于一种简单的方法,涉及磁化和检测血红蛋白中的铁原子。涉及的参数包括氧合血红蛋白和脱氧血红蛋白的磁化率,外部磁场超过1特斯拉。从物理建模和仿真,获得的图描绘了血红蛋白浓度对Fe原子数及其磁化强度的影响。这使得能够设计非侵入式血红蛋白测量传感器装置。这种简单的物理模型和模拟的独特性在于它能够产生专门设计的用于测量血红蛋白浓度的设备模型。这与其他专注于血流脉冲测量的研究不同;这项研究的结果为可以开发用于医学诊断研究和设备开发的简单物理方程的好处提供了新的见解。
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