Abstract:
Over the past few years, there has been a surge in interest regarding the connection between sleep duration and quality, sleep disorders, mainly Obstructive sleep apnoea (OSA) and Vitamin D. There is growing evidence to support a new role of Vitamin D in the maintenance and regulation of optimal sleep. Furthermore, a notable link has been identified between OSA and a decrease in serum Vitamin D levels, which appears to intensify as the severity of sleep apnea worsens. Vitamin D status could also potentially serve as a mediator or provide an explanation for the association between OSA and cardiometabolic morbidity, but the current state of research in this area is inadequate. Studies have indicated that the supplementation of Vitamin D can optimize sleep quality, presenting more proof of the connection between insufficient vitamin D levels and sleep disorders. However, it is unclear whether low serum Vitamin D levels are a contributing factor to OSA development or if OSA predisposes individuals to Vitamin D deficiency. As a result, various studies have endeavored to examine the complex relationship between OSA and Vitamin D deficiency. In children and adolescents, while data is limited, there seems also to be a link between sleep disorders and Vitamin D levels. Therefore, the objective of this review is to provide a comprehensive overview of the current evidence on the association between Vitamin D and sleep disorders in both adults and children.
摘要:
在过去的几年里,人们对睡眠持续时间和质量之间的联系的兴趣激增,睡眠障碍,主要是阻塞性睡眠呼吸暂停(OSA)和维生素D。越来越多的证据支持维生素D在维持和调节最佳睡眠中的新作用。此外,OSA与血清维生素D水平下降之间存在显着联系,随着睡眠呼吸暂停的严重程度恶化,这种情况似乎会加剧。维生素D状态也可能作为介质或为OSA和心脏代谢疾病之间的关联提供解释。但是目前这方面的研究还不够。研究表明,补充维生素D可以优化睡眠质量,提供更多维生素D水平不足与睡眠障碍之间联系的证据。然而,目前尚不清楚低血清维生素D水平是否是OSA发展的一个促成因素,或者OSA是否会导致个体维生素D缺乏.因此,各种研究都在努力研究OSA与维生素D缺乏之间的复杂关系。在儿童和青少年中,虽然数据有限,睡眠障碍和维生素D水平之间似乎也有联系。因此,本综述的目的是全面概述目前关于维生素D与成人和儿童睡眠障碍之间关联的证据.