Abstract：
OBJECTIVE: To examine outcomes of oocyte retrievals completed by Reproductive Endocrinology and Infertility (REI) fellows versus faculty physicians.
METHODS: This retrospective cohort study examined patients who underwent oocyte retrievals at Mayo Clinic from July 15, 2009, to December 15, 2016. The primary outcome was the oocyte retrieval rate (ORR) calculated per retrieval as the number of oocytes retrieved per follicles aspirated. The Wilcoxon signed-rank test was used to compare follicle and oocyte counts and ORR between fellows and faculty during the same bilateral retrieval.
RESULTS: The study cohort included the first bilateral retrieval from 845 unique patients completed by 11 fellows and seven faculty. The median ORR was not statistically different for fellows and faculty (0.79 versus 0.80, p = 0.46). To assess for a learning curve, the outcomes of seven fellows who completed at least 80 retrievals in their first year were examined as four chronologically ordered sets of 20. When these sets were compared to the faculty physician mean ORR, no significant differences were found (p-values of 0.69, 0.69, 0.81, and 0.81, respectively).
CONCLUSIONS: There were no significant differences in oocyte retrieval rates between fellows versus faculty over a 7-year period, with no significant learning curve observed. These findings suggest that fellows possess the requisite skills for successful oocyte retrieval upon entering REI fellowship following their OB/GYN residency. However, this does not diminish the critical role of comprehensive fellowship training and close supervision, especially in initial and complex cases.
METHODS: This retrospective cohort study examined patients who underwent oocyte retrievals at Mayo Clinic from July 15, 2009, to December 15, 2016. The primary outcome was the oocyte retrieval rate (ORR) calculated per retrieval as the number of oocytes retrieved per follicles aspirated. The Wilcoxon signed-rank test was used to compare follicle and oocyte counts and ORR between fellows and faculty during the same bilateral retrieval.
RESULTS: The study cohort included the first bilateral retrieval from 845 unique patients completed by 11 fellows and seven faculty. The median ORR was not statistically different for fellows and faculty (0.79 versus 0.80, p = 0.46). To assess for a learning curve, the outcomes of seven fellows who completed at least 80 retrievals in their first year were examined as four chronologically ordered sets of 20. When these sets were compared to the faculty physician mean ORR, no significant differences were found (p-values of 0.69, 0.69, 0.81, and 0.81, respectively).
CONCLUSIONS: There were no significant differences in oocyte retrieval rates between fellows versus faculty over a 7-year period, with no significant learning curve observed. These findings suggest that fellows possess the requisite skills for successful oocyte retrieval upon entering REI fellowship following their OB/GYN residency. However, this does not diminish the critical role of comprehensive fellowship training and close supervision, especially in initial and complex cases.
摘要：
目的：检查由生殖内分泌学和不孕症（REI）研究员与教员医师完成的卵母细胞检索结果。
方法：这项回顾性队列研究检查了2009年7月15日至2016年12月15日在梅奥诊所接受卵母细胞回收的患者。主要结果是每次取出的卵母细胞取出率（ORR），计算为每个卵泡取出的卵母细胞数。在相同的双侧检索过程中，使用Wilcoxon符号秩检验比较研究员和教师之间的卵泡和卵母细胞计数以及ORR。
结果：研究队列包括由11名研究员和7名教师完成的845名独特患者的首次双边检索。研究员和教职员工的ORR中位数没有统计学差异（0.79对0.80，p=0.46）。要评估学习曲线，7名研究员在第一年内完成至少80次检索的结果被视为按时间顺序排列的4组,每组20次.当这些集合与教员医生的平均ORR进行比较时，没有发现显著差异(p值分别为0.69,0.69,0.81和0.81).
结论：在7年的时间内，研究员与教师之间的卵母细胞提取率没有显着差异，没有观察到明显的学习曲线。这些发现表明，研究员在获得OB/GYN居留权后进入REI研究金后，具有成功提取卵母细胞的必要技能。然而,这并没有削弱全面研究金培训和密切监督的关键作用，特别是在最初和复杂的情况下。
方法：这项回顾性队列研究检查了2009年7月15日至2016年12月15日在梅奥诊所接受卵母细胞回收的患者。主要结果是每次取出的卵母细胞取出率（ORR），计算为每个卵泡取出的卵母细胞数。在相同的双侧检索过程中，使用Wilcoxon符号秩检验比较研究员和教师之间的卵泡和卵母细胞计数以及ORR。
结果：研究队列包括由11名研究员和7名教师完成的845名独特患者的首次双边检索。研究员和教职员工的ORR中位数没有统计学差异（0.79对0.80，p=0.46）。要评估学习曲线，7名研究员在第一年内完成至少80次检索的结果被视为按时间顺序排列的4组,每组20次.当这些集合与教员医生的平均ORR进行比较时，没有发现显著差异(p值分别为0.69,0.69,0.81和0.81).
结论：在7年的时间内，研究员与教师之间的卵母细胞提取率没有显着差异，没有观察到明显的学习曲线。这些发现表明，研究员在获得OB/GYN居留权后进入REI研究金后，具有成功提取卵母细胞的必要技能。然而,这并没有削弱全面研究金培训和密切监督的关键作用，特别是在最初和复杂的情况下。
