关键词: Web of Science bibliometric analysis ferroptosis nanoscience

来  源:   DOI:10.1002/hcs2.5   PDF(Pubmed)

Abstract:
UNASSIGNED: Ferroptosis has been widely investigated as an emerging drug target, while its combination with nanoscience provides bourgeoning application prospects. The development of ferroptosis regulating nanomedicines have attracted worldwide attentions in recent years. It would be meaningful to describe the relevant publication paradigm.
UNASSIGNED: Herein, a bibliometric analysis was performed using the database of Web of Science Core Collection to clarify the publication paradigm. The development of related publications in the last 6 years was described, and the revolutionary trends were figured out. Ultimately, the possible future exploration directions were proposed.
UNASSIGNED: The bibliometric analysis of 327 documents of interest indicated that the main research focus was in multiple fields including Materials science, Science & technology, Chemistry, and Pharmacology & pharmacy. With widely cooperation and strong funding, the researchers from Chinese organizations contributed most of publications, followed with United States and Australia. Cocitation analysis revealed that several original papers reported the key molecular mechanisms of ferroptosis were considered as the foundation for subsequent studies, and some nanomedicines-related documents were taken as examples and discussed. Mining results showed that the mechanism evaluation of ferroptosis regulation therapy for cancer treatment was the hotspot. Then, several possible future explorations of ferroptosis-related nanoscience were presented and discussed.
UNASSIGNED: The bibliometric profile of nanoscience-ferroptosis research was analyzed in detail. We believe that the bibliometric analysis could act as a robust method for explicating the publication paradigm as a certain field.
摘要:
Ferroptosis作为一种新兴的药物靶标已被广泛研究,而它与纳米科学的结合提供了广阔的应用前景。近年来,调节铁死亡的纳米药物的发展引起了全世界的关注。描述相关的出版范式将是有意义的。
这里,使用WebofScienceCoreCollection的数据库进行了文献计量学分析,以阐明出版范式.介绍了近6年来相关出版物的发展情况,革命趋势被弄清楚了。最终,提出了未来可能的勘探方向。
对327份文件的文献计量分析表明,主要研究重点是包括材料科学在内的多个领域,科学技术,化学,药理学和药学。凭借广泛的合作和强大的资金,来自中国组织的研究人员贡献了大部分出版物,其次是美国和澳大利亚。共合分析显示,几篇原始论文报道了铁凋亡的关键分子机制,被认为是后续研究的基础。并以一些与纳米药物相关的文献为例进行了讨论。挖掘结果表明,铁凋亡调节疗法在癌症治疗中的机制评估是热点。然后,提出并讨论了与铁凋亡相关的纳米科学的几种可能的未来探索。
详细分析了纳米科学-铁性研究的文献计量学概况。我们认为,文献计量分析可以作为一种可靠的方法,将出版范式解释为某个领域。
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