关键词: Cancellous and cortical bone grafts Dog Erythropoietin Non-union Radius and ulna fracture

Mesh : Animals Dogs / injuries Erythropoietin / therapeutic use Bone Transplantation / veterinary Fractures, Ununited / veterinary surgery Dog Diseases / surgery Ulna Fractures / veterinary surgery Male Radius Fractures / veterinary surgery Female

来  源:   DOI:10.5455/OVJ.2024.v14.i5.25   PDF(Pubmed)

Abstract:
UNASSIGNED: Fractures with large bone defects and non-unions are a great challenge for veterinary orthopaedists. In small dog breeds, this complication is commonly encountered in fractures of the radius and ulna due to poorer vascularisation of the distal antebrachium region.
UNASSIGNED: A case of radius/ulnar non-union in a 1.5-year-old Pinscher occurring after trauma and two successive unsuccessful osteosyntheses is described. During the operative revision, after the removal of existing bone implants, the bone defect was filled with cortical autologous bone graft. Autocancellous bone mixed with erythropoietin was applied proximally and distally to the cortical autograft for stimulation of bone healing. The post-operative period was without complications. As early as the 9th post-operative week, the animal was able to bear weight on the limb, without signs of lameness, pain, and swelling. Radiologically, a very good bridging of the graft was observed. Fifteen weeks after the operative revision, the fracture was completely healed with excellent clinical outcome.
UNASSIGNED: The application of autogenous cortical bone graft and cancellous autograft mixed with erythropoietin demonstrated an excellent therapeutic effect and resulted in complete regeneration of the large bone defect over a 15-week period.
摘要:
具有较大骨缺损和不愈合的骨折对兽医骨科医师来说是一个巨大的挑战。在小型犬种中,这种并发症通常发生在桡骨和尺骨骨折中,原因是前臂远端血管形成较差.
描述了一个1.5岁的Pinscher在创伤和两次连续不成功的骨合成后发生的桡骨/尺骨不愈合的情况。手术翻修期间,在移除现有的骨植入物后,骨缺损填充皮质自体骨移植。将与促红细胞生成素混合的自体松质骨近端和远端应用于皮质自体移植物,以刺激骨愈合。术后无并发症。早在术后第9周,这只动物能够承受四肢的重量,没有跛行的迹象,疼痛,和肿胀。放射学上,观察到移植物的非常好的桥接。手术翻修后15周,骨折完全愈合,临床效果良好。
应用自体皮质骨移植物和松质骨自体移植物与促红细胞生成素混合显示出优异的治疗效果,并导致在15周内完全再生大骨缺损。
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