关键词: cardiovascular disease disparities maternal health preeclampsia race/ethnicity socioeconomic status

来  源:   DOI:10.1016/j.jacadv.2022.100062   PDF(Pubmed)

Abstract:
UNASSIGNED: Preeclampsia is associated with higher in-hospital cardiovascular events and mortality with known disparities by race/ethnicity, but data on the interaction between income and these outcomes remain limited.
UNASSIGNED: This study investigated racial and socioeconomic disparities in cardiovascular outcomes of preeclampsia at delivery hospitalizations.
UNASSIGNED: We analyzed National Inpatient Sample data using International Classification of Diseases-9th Revision/-10th Revision codes between 2004 and 2019. We identified a total of 2,436,991 delivery hospitalizations with preeclampsia/eclampsia as a primary diagnosis representing White (43.1%), Black (18.4%), Hispanic (18.7%), and Asian or Pacific Islander (A/PI; 3.3%) women. We stratified the population based on median household income (low income, medium income, and high income). Logistic regression and propensity-matched analysis were used for reporting outcomes adjusted for age, hospital region, and baseline comorbidities.
UNASSIGNED: Black Hispanic, and A/PI women with preeclampsia had higher in-hospital mortality compared with White women across all groups of income. Hispanic women had lower odds of peripartum cardiomyopathy (PPCM) compared with White women. A significant interaction effect was observed with race/ethnicity and median household income for in-hospital mortality and PPCM with preeclampsia. Furthermore, high-income Black women had higher odds of PPCM, stroke, acute kidney injury, heart failure, cardiac arrhythmia, and venous thromboembolism compared with low-income White women.
UNASSIGNED: Women with preeclampsia experience significant racial/ethnic and socioeconomic disparities in inpatient mortality and cardiovascular outcomes at delivery. Across all income groups, Black, Hispanic, and A/PI women experience higher odds of in-hospital mortality compared with White women. Furthermore, high-income Black women had greater odds of many CV complications compared with low-income White women.
摘要:
先兆子痫与更高的院内心血管事件和死亡率相关,已知种族/民族之间存在差异。但是关于收入和这些结果之间相互作用的数据仍然有限。
这项研究调查了先兆子痫在分娩住院时心血管结局的种族和社会经济差异。
我们使用国际疾病分类-第9次修订/-第10次修订代码在2004年至2019年之间分析了全国住院患者样本数据。我们确定了总共2,436,991例先兆子痫/子痫的分娩住院为主要诊断,代表怀特(43.1%)。黑色(18.4%),西班牙裔(18.7%),亚洲或太平洋岛民(A/PI;3.3%)妇女。我们根据家庭收入中位数(低收入,中等收入,和高收入)。Logistic回归和倾向匹配分析用于报告根据年龄调整的结果,医院区域,和基线合并症。
西班牙裔黑人,与所有收入组的白人女性相比,患有先兆子痫的A/PI女性的住院死亡率更高.与白人女性相比,西班牙裔女性患围产期心肌病(PPCM)的几率较低。观察到种族/民族和家庭收入中位数对住院死亡率和PPCM伴先兆子痫的显着交互作用。此外,高收入黑人女性患PPCM的几率更高,中风,急性肾损伤,心力衰竭,心律失常,与低收入白人女性相比,静脉血栓栓塞症。
患有先兆子痫的妇女在分娩时住院死亡率和心血管结局方面经历显著的种族/族裔和社会经济差异。在所有收入群体中,黑色,西班牙裔,与白人女性相比,A/PI女性住院死亡率较高。此外,与低收入白人女性相比,高收入黑人女性发生心血管并发症的几率更大.
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