Abstract：
UNASSIGNED: Comorbidities increase susceptibility to severe coronavirus disease 2019 (COVID-19) infections, but limited information has been published regarding HIV and COVID-19 co-infections. This study explored the relationships among socioeconomic characteristics, sexual behaviors, and COVID-19 infection rates among Korean men who have sex with men (MSMs) who are also living with HIV.
UNASSIGNED: Data were collected through a web survey aimed at members of the largest gay portal site in Korea, supported by the National Research Foundation of Korea (n=1,005). The primary independent variables included COVID-19-related vaccinations and sexual behaviors. The dependent variable was the incidence of COVID-19 infection among respondents during the pandemic. For statistical analysis, hierarchical multiple logistic regression was performed, controlling for potential confounding variables.
UNASSIGNED: Model I indicated that older MSM were less likely to contract COVID-19 (adjusted odds ratio [aOR], 0.975; 95% CI, 0.962-0.989). Model II demonstrated that HIV-positive MSM were nearly twice as likely to be infected with COVID-19 compared to their HIV-negative counterparts (aOR, 1.974; 95% CI, 1.144-3.408). Furthermore, even after accounting for COVID-19 vaccination status in model III, HIV-positive MSM continued to show a higher risk of infection (aOR, 1.934; 95% CI, 1.118-3.346).
UNASSIGNED: The findings of this study indicate that HIV-positive MSM are at an increased risk of contracting COVID-19, even when their vaccination status is considered. Therefore, it is essential to prioritize the prevention of COVID-19 infections in HIV-positive individuals by administering appropriate antiretroviral therapy and ensuring adherence to public health guidelines.
UNASSIGNED: Data were collected through a web survey aimed at members of the largest gay portal site in Korea, supported by the National Research Foundation of Korea (n=1,005). The primary independent variables included COVID-19-related vaccinations and sexual behaviors. The dependent variable was the incidence of COVID-19 infection among respondents during the pandemic. For statistical analysis, hierarchical multiple logistic regression was performed, controlling for potential confounding variables.
UNASSIGNED: Model I indicated that older MSM were less likely to contract COVID-19 (adjusted odds ratio [aOR], 0.975; 95% CI, 0.962-0.989). Model II demonstrated that HIV-positive MSM were nearly twice as likely to be infected with COVID-19 compared to their HIV-negative counterparts (aOR, 1.974; 95% CI, 1.144-3.408). Furthermore, even after accounting for COVID-19 vaccination status in model III, HIV-positive MSM continued to show a higher risk of infection (aOR, 1.934; 95% CI, 1.118-3.346).
UNASSIGNED: The findings of this study indicate that HIV-positive MSM are at an increased risk of contracting COVID-19, even when their vaccination status is considered. Therefore, it is essential to prioritize the prevention of COVID-19 infections in HIV-positive individuals by administering appropriate antiretroviral therapy and ensuring adherence to public health guidelines.
摘要：
■合并症增加了对2019年严重冠状病毒病（COVID-19）感染的易感性，但有关HIV和COVID-19共感染的信息有限。本研究探讨了社会经济特征之间的关系，性行为,和COVID-19感染率在韩国男男性行为者(MSM)中也感染了艾滋病毒。
■数据是通过一项针对韩国最大同性恋门户网站成员的网络调查收集的，由韩国国家研究基金会（n=1,005）支持。主要独立变量包括与COVID-19相关的疫苗接种和性行为。因变量是大流行期间受访者中COVID-19感染的发生率。为了进行统计分析，进行分层多元逻辑回归，控制潜在的混杂变量。
■模型I表明，较老的MSM不太可能收缩COVID-19(调整后的赔率比[aOR]，0.975；95%CI，0.962-0.989）。模型II表明，与HIV阴性的MSM相比，HIV阳性的MSM感染COVID-19的可能性几乎是其两倍(aOR，1.974；95%CI，1.144-3.408）。此外，即使考虑到模型III中的COVID-19疫苗接种状态，HIV阳性MSM继续显示出更高的感染风险(aOR，1.934；95%CI，1.118-3.346）。
■这项研究的结果表明，即使考虑到他们的疫苗接种状况，HIV阳性MSM感染COVID-19的风险也增加。因此,必须优先预防HIV阳性者的COVID-19感染,方法是给予适当的抗逆转录病毒治疗,并确保遵守公共卫生指南.
■数据是通过一项针对韩国最大同性恋门户网站成员的网络调查收集的，由韩国国家研究基金会（n=1,005）支持。主要独立变量包括与COVID-19相关的疫苗接种和性行为。因变量是大流行期间受访者中COVID-19感染的发生率。为了进行统计分析，进行分层多元逻辑回归，控制潜在的混杂变量。
■模型I表明，较老的MSM不太可能收缩COVID-19(调整后的赔率比[aOR]，0.975；95%CI，0.962-0.989）。模型II表明，与HIV阴性的MSM相比，HIV阳性的MSM感染COVID-19的可能性几乎是其两倍(aOR，1.974；95%CI，1.144-3.408）。此外，即使考虑到模型III中的COVID-19疫苗接种状态，HIV阳性MSM继续显示出更高的感染风险(aOR，1.934；95%CI，1.118-3.346）。
■这项研究的结果表明，即使考虑到他们的疫苗接种状况，HIV阳性MSM感染COVID-19的风险也增加。因此,必须优先预防HIV阳性者的COVID-19感染,方法是给予适当的抗逆转录病毒治疗,并确保遵守公共卫生指南.
